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Screening Libraries
Polygonum multiflorum
A unique collection of 18 Polygonum multiflorum for high throughput screening (HTS), high content screening (HCS) and New drug research
Cat. Size Price Stock
P206121mg/well * 18 CompoundsInquiry In stock
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P20612100uL/well (10mM solution) * 18 CompoundsInquiry In stock
*You can select compounds, quantities, format (dry/solid or DMSO) and plate map to meet your specific requirement.
Contact Us
E-mail manager@chemfaces.com
Tel (0086)-27-8423-7683
Shelf Life (0086)-27-84254680
ManufacturerWuhan ChemFaces Biochemical Co., Ltd.
Package & Storage
Container 96 Well Format Sample
Storage Protected from air and light, refrigerate or freeze(2-8 °)
Shelf Life 24 months (2-8 °)
Intended UseFor research use only. Not for human use. Not sell to patients
Description & Advantages
1. The products in the ChemFaces screening libraries are all from plants.
2. The biological activities or pharmacological activities of all the ChemFaces products are derived from the databases of all over the world the latest literatures, you can according to the product manuals on our website to access the relevant literatures, hope that our informations can give some inspirations and help to your research.
3.The collections of unique natural products, which include antioxidants, anti-inflammatory, antibacterial, anticancer, and ect. Can be used for high throughput screening (HTS) and high content screening (HCS), is to help you carry out new drug screening, the emergence of new indications and other professional tools.
4.Structurally diverse, medicinally active, and cell permeable, NMR and HPLC validated to ensure high purity.
5. ChemFaces offers customized bioactive screening libraries , whereby you choose the specific compounds you want in the library, the quantities, plate map, concentration, and format (dry/solid or DMSO solution).
Natural Products
Catalog No. Information
CFN99995 2,3,5,4'-Tetrahydroxyl diphenylethylene-2-O-glucoside

2,3,5,4'-Tetrahydroxyldiphenylethylene-2-O-glucoside(TSG) has potential to the prevention and treatment of Alzheimer's diseases, it not only prevents over-expression of α-synuclein at an early stage, but also reverses the increased expression of α-synuclein and inhibits the aggregation at the late stage of Tg mice. TSG suppresses PDGF-BB-induced PASMCs proliferation is associated with an inhibition of AKT / GSK3β signaling pathways. TGS, emodin and physcion also have the lipid regulation activity to an overall synergy.
CFN99646 Catechin

Catechin, a cyclooxygenase-1 (COX-1) inhibitor with an IC50 of 1.4 μM, which has antiangiogenic, antitumor, antioxidant, UV-protective, anti-aging, phytotoxic, antimicrobial, and antiviral effects. Catechin shows its potential as biobased active packaging for fatty food, and exerts cardioprotection through treating many kinds of angiocardiopathy.
CFN99624 Gallic acid

Gallic acid, is a histone acetyltransferase inhibitor and a potent inhibitor of brush border sucrase and other disaccharidases, which has powerful antioxidant, anti-tumor, and anti-tyrosinase activities. It can potentially interfere with the digestive functions of the intestine. It can efficiently block neuronal cell death by downregulating the expression of cytokines and the in vivo levels of NF-κB acetylation, is a possible therapeutic approach for alleviating the inflammatory progression of Alzheimer disease.
CFN99571 (-)-Gallocatechin gallate

(-)-Gallocatechin gallate has cancer-preventive activities, it can precipitate cholesterol, decreasee osteoclastogenesis at 20 microM.
CFN99569 (-)-Epigallocatechin gallate

(-)-Epigallocatechin Gallate is an antioxidant polyphenol flavonoid form green tea, and inhibits the activation of EGFR, HER2 and HER3, with antitumor activity. (-)-Epigallocatechin gallate treatment enduring to cardio protection at mitochondrial level, it has protective effects against βA-induced neuronal apoptosis through scavenging reactive oxygen species, which may be beneficial for the prevention of Alzheimer's disease.
CFN99157 Rhein

Rhein has many pharmacological effects, including epatoprotective, nephroprotective, anti-inflammatory, antioxidant, anticancer, and antimicrobial activities, it has been proved effective in treatment of experimental diabetic nephropathy , one of the mechanism is the Inhibition of the hexosamine pathway. Rhein has protective effect on liver injury, the mechanisms possibly contribute to its action of antioxidant and anti-inflammatory activity, also associated with its effect of inhibiting TGF-β1 and suppressing the activation of hepatic stellate cells.
CFN98848 Physcion

Physcion shows cytotoxic effect on human cervical carcinoma HeLa cells and its apoptosis induction in HeLa cells was investigated by the expressions of p53, p21, Bax, Bcl-2, caspase-9, and caspase-3 proteins. Physcion controls powdery mildew mainly through changing the expression of defence-related genes, and especially enhancing expression of leaf-specific thionin in barley leaves.
CFN98834 Emodin

Emodin has neuroprotective and antidepressant activity, can up-regulate GR and BDNF levels in hippocampus; it also has significant anti-neoplastic activity against bladder cancer cells and myeloid leukemia, by suppressing tumor necrosis factor-alpha (TNF-α), interleukin-6 (IL-6), iNOS and COX-2 expression. Emodin has protective effects, may be related to the inhibition of CCL5 expression and subsequent cell stress/inflammatory events possibly mediated by activation of MAPK signaling pathways.
CFN98791 Resveratrol

Resveratrol, a natural polyphenol that possesses anti-oxidant, anti-inflammatory, cardioprotective, blood-sugar-lowering, antiaging, and anti-cancer properties. It has a wide spectrum of targets including cyclooxygenases(i.e. COX, IC50=1.1 μM), lipooxygenases(LOX, IC50=2.7 μM, kinases, sirtuins, c-IAP1, c-IAP2, livin and XIAP. Resveratrol regulates gene transcription via activation of the stimulus-regulated protein kinases Raf and ERK and the stimulus-responsive transcription factors TCF and Egr-1.
CFN98781 Epicatechin

(−)Epicatechin is a flavonoid present in cocoa, green tea and red wine. It is a strong antioxidant, has antinociceptive, insulin mimic actions and improves heart health; it has the potential to increase CREB-regulated gene expression and increase GluR2 levels and thus modulate neurotransmission, plasticity and synaptogenesis. (-)-Epicatechin inhibits cyclooxygenase-1 (COX-1) with an IC50 of 3.2 μM; it inhibits the IL-1β-induced expression of iNOS by blocking the nuclear localization of the p65 subunit of NF-κB.