Screening Libraries
| Cat. | Size | Price | Stock | |
| P20319 | 1mg/well * 11 Compounds | Inquiry | In stock | Contact Us |
| P20319 | 100uL/well (10mM solution) * 11 Compounds | Inquiry | In stock |
| manager@chemfaces.com | |
| Tel | (0086)-27-8423-7683 |
| Shelf Life | (0086)-27-84254680 |
| Manufacturer | Wuhan ChemFaces Biochemical Co., Ltd. |
| Container | 96 Well Format Sample |
| Storage | Protected from air and light, refrigerate or freeze(2-8 °) |
| Shelf Life | 24 months (2-8 °) |
| Intended Use | For research use only. Not for human use. Not sell to patients |
| 1. The products in the ChemFaces screening libraries are all from plants. |
| 2. The biological activities or pharmacological activities of all the ChemFaces products are derived from the databases of all over the world the latest literatures, you can according to the product manuals on our website to access the relevant literatures, hope that our informations can give some inspirations and help to your research. |
| 3.The collections of unique natural products, which include antioxidants, anti-inflammatory, antibacterial, anticancer, and ect. Can be used for high throughput screening (HTS) and high content screening (HCS), is to help you carry out new drug screening, the emergence of new indications and other professional tools. |
| 4.Structurally diverse, medicinally active, and cell permeable, NMR and HPLC validated to ensure high purity. |
| 5. ChemFaces offers customized bioactive screening libraries , whereby you choose the specific compounds you want in the library, the quantities, plate map, concentration, and format (dry/solid or DMSO solution). |
| Catalog No. | Information |
| CFN99734 | Biochanin A Biochanin A, an O-methylated natural isoflavonoid classified as phytoestrogen, is a naturally occurring fatty acid amide hydrolase (FAAH) inhibitor, which inhibits FAAH with IC50s of 1.8, 1.4 and 2.4 μM for mouse, rat, and human FAAH, respectively. Biochanin A has hypoglycemic, antilipemic,anti-tumorigenesis, anti-oxidation, and anti-inflammatory properties, it also has neuroprotective effects in cerebral ischemia/reperfusion by inhibiting inflammatory response and the inactivation of p38 signaling pathway. Biochanin A could inhibit Methicillin-resistant Staphylococcus aureus efflux system through reducing pathogen' s expression of nor A and norA protein. |
| CFN99101 | Daidzin Daidzin is a potent, selective aldehyde dehydrogenase 2 (ALDH2,IC50 = 80 nM) inhibitor, which has antiallergic anti-oxidant, anti-carcinogenic, antithrombotic,and anti-atherosclerotic activities, It has preventive effect on bone loss in ovariectomized rats appears to be due to suppression of bone turnover. A mixture of daidzin and glycitin has anti-obese and anti-diabetic effects. |
| CFN98794 | trans-4-Hydroxycinnamic acid Trans-4-hydroxycinnamic acid has antimicrobial, and anti-oxidant activities. |
| CFN98774 | Daidzein Daidzein is a natural isoflavone phytoestrogen and a PPAR activator, used as a component of foods and dietary supplements, it should be a promising feed additive for production of high-quality beef meat. Daidzein has antitumor, anti-fibrotic, anti-bone loss, and anti-inflammatory effects. Daidzein inhibits TLR4-MyD88-NF-κB pathway. |
| CFN98735 | Isorhamnetin Isorhamnetin, a natural flavonol aglycon, is a tyrosinase inhibitor and has anti-adipogenic, cardioprotective, anti-tumor, and antioxidant activities. it inhibits the H(2)O(2)-induced activation of the intrinsic apoptotic pathway via ROS scavenging and ERK inactivation, it inhibits NF-κB signaling. Isorhamnetin prevents angiotensin II (AngII)-induced endothelial dysfunction by inhibiting the overexpression of p47(phox) and the subsequent increases O2-production, resulting in increased nitric oxide bioavailability. |
| CFN98681 | Genistein Genistein, a phytoestrogen found in soy products, is a highly specific inhibitor of protein tyrosine kinase (PTK) which blocks the mitogenic effect mediated by EGF on NIH-3T3 cells with IC50 of 12μM or by insulin with IC50 of 19 μM. Genistein has neuroprotective, antitumor effects, it modulates the expression of NF-κB and MAPK (p-38 and ERK1/2), thereby attenuating d-Galactosamine induced fulminant hepatic failure in Wistar rats. |
| CFN98117 | Beta-Carotene Beta Carotene is an organic compound and classified as a terpenoid. It is a precursor (inactive form) of vitamin A. Beta-Carotene has antioxidant activity, anti-cancer, and antiapoptotic activities, it has protective effects against gamma-radiation-induced in vivo chromosomal damage. Dietary supplementation of carotenoids may act as moderate hypocholesterolemic agents, secondary to their inhibitory effect on macrophage 3-hydroxy-3-methyl glutaryl coenzyme A (HMGCoA) reductase, the rate limiting enzyme in cholesterol synthesis. |
| CFN90250 | Genistin Supplementation of Genistin alone or with selenium provides antioxidant defense with high-potential chemopreventive activity against DMBA-induced mammary tumors more than selenium alone.Intravitreal injection of Genistin is safe and effective in reducing traumatic PVR in clinical treatment. |
| CFN97016 | Isosativan Isosativan, sativan and vestitol are isoflavan phytoalexins. |
| CFN97005 | Sissotrin Sissotrin can impair glucose tolerance. |
