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  • Bioactive Products
    Catalog No. Information
    CFN99343 Bi-linderone

    1. Bi-linderone shows significant activity against glucosamine-induced insulin resistance in HepG2 cells at a concentration of 1 microg/mL.
    CFN99350 Linderaspirone A

    1. Linderaspirone A shows significant activity against glucosamine-inducedinsulin resistance.
    CFN99751 (-)-Licarin B

    Licarin B can improve insulin sensitivity via PPARγ and activation of GLUT4 in the IRS-1/PI3K/AKT pathway in 3T3-L1 adipocytes, it as a promising bioactive for insulin resistance and associated complications through its partial PPARγ activity.
    CFN99974 Ginsenoside Re

    Ginsenoside Re is a major ginsenoside in ginseng and belongs to 20(S)-protopanaxatriol group. It has diverse in vitro and in vivo effects, including anti-diabetic, vasorelaxant, antihyperlipidemic, anti-ischemic, angiogenic, antioxidant, and anti-inflammation actions. It also exhibits potent neuroprotective effects against neuroinflammation in a murine model of ALS. Re increases HCAEC outward current via SKCa channel activation; it also increases the proliferation of CD4+ T cells with decreases cell death, and enhances viability of CD4+T cells through the regulation of IFN-γ-dependent autophagy activity.
    CFN98073 Agrimonolide

    1. Agrimonolide exerts anti-inflammatory activity, at least in part, via suppressing LPS-induced activation of JAK-STATs and p38 MAPKs signaling pathway.
    2. Agrimonolide is a potential α1 adrenergic receptor antagonist .
    3. Agrimonolide and desmethylagrimonolide can effectively increase insulin-mediated glycogen level in heptocytes, they may play an important role in regulating glucose metabolism in insulin-resistance HepG2 cells and could be developed as a promising natural material for diabetes prevention and treatment.