|A unique collection of 34 Anti-obesity natural compounds|
|Catalog No:||B562|| Anti-obesity Compound Library
|Size:||1mg/well * 34 Compounds|
2mg/well * 34 Compounds
1. Galanolactone shows cytotoxic activity .
2. Galanolactone has anti-5-HT effect, a diterpenoid isolated from ginger, is related to antagonism of 5-HT3 receptors.
3. Galanolactone exerts anti-obesity effect through down regulation of adipogenic transcription factors and adipogenic marker genes.
4. Galanolactone has inhibit nitric oxide production with IC(50) values ranging from 5.5 to 28.5 μM.
Glycitin has antibacterial, antiviral, anti-obese,anti-diabetic and estrogenic activities and may exert preventative effects on alcoholism, osteonecrosis,cardiovascular and cerebrovascular diseases and some types of cancer. It has a protective effect on skin aging by inhibiting of MMP-1 and increasing of collagen through ERK/JNK/P38 down-regulation, shows good inhibitory effect on α-glucosidase with IC50 of 0.5646 mg/mL.
Asperuloside exerts its anti-inflammatory effect in correlation with inhibition of a pro-inflammatory mediator through suppressing nuclear factor kappa-B (NF-κB) nuclear translocation and MAPK phosphorylation in a dose-dependent manner. Chronic administration of Asperuloside stimulates anti-obesity and anti-metabolic syndrome activity in HFD-fed rats across several organs, similar to Eucommia leaf extract (ELE) administration.
(-)-Epigallocatechin Gallate is an antioxidant polyphenol flavonoid form green tea, and inhibits the activation of EGFR, HER2 and HER3, with antitumor activity. (-)-Epigallocatechin gallate treatment enduring to cardio protection at mitochondrial level, it has protective effects against βA-induced neuronal apoptosis through scavenging reactive oxygen species, which may be beneficial for the prevention of Alzheimer's disease.
Zingerone has anti-mutagenic, anti-carcinogenic, anti-obesity,anti-oxidative and anti-inflammatory activities. Zingerone can be recommended as a supplement to shrimp feed to increase growth, immunity, and disease resistance against the pathogen, V.alginolyticus , use of zingerone as appetizer and immunostimulant in shrimp is promising. It could as potential phytotherapeutic agent which in future can be employed to formulate preventive strategies against biofilm associated infections caused by P.aeruginosa.