• ChemFaces is a professional high-purity natural products manufacturer.
  • Product Intended Use
  • 1. Reference standards
  • 2. Pharmacological research
  • 3. Inhibitors
  • Home
  • Natural Products
  • Bioactive
  • Screening Libraries
  • Hot Products
  • Plant Catalog
  • Customer Support
  • Product Use Citation
  • About Us
  • Contact Us
  • Bioactive Products
    Catalog No. Information
    CFN99750 Dehydrodiisoeugenol

    1. Dehydrodiisoeugenol has anti-inflammatory activity.
    (1) Dehydrodiisoeugenol inhibited the expression of the COX-2 in RAW264.7 murine macrophages stimulated with LPS.
    (2) Dehydrodiisoeugenol inhibited LPS-stimulated phosphorylation-dependent proteolysis of inhibitor κB-α and transcriptional activity of NF-κB in the cells.
    2. Dehydrodiisoeugenol can cross the blood-brain barrier rapidly and might be one of the main bioactive substances of nutmeg, the results provide fundamental data for evaluating the effects of DDIE on the central nervous system and to be developed into an effective anxiogenic agent.
    CFN90589 Myristicin

    1. Myristicin may antagonize the anxiolytic effects of midazolam, increase anxiety, and affect motor movements.
    2. Myristicin can alter mitochondrial membrane function, induce apoptosis and modulate gene expression in human leukaemia K562 cells.
    3. Myristicin can induce apoptosis as characterised by alterations in the mitochondrial membrane potential, cytochrome c release, caspase-3 activation, PARP-cleavage and DNA fragmentation.
    4. Myristicin has anti-cholinergic, antibacterial,and hepatoprotective effects.
    5. Myristicin has anti-inflammatory properties related with its inhibition of NO, cytokines,chemokines, and growth factors in dsRNA-stimulated macrophages via the calcium pathway.