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Bioactive Products
Cytotoxic Compound Library
A unique collection of 129 Cytotoxic natural compounds used for Cytotoxic research
Catalog No: B913 Cytotoxic Compound Library
Screening Details
Size: 1mg/well * 129 Compounds
2mg/well * 129 Compounds
Cat. No. Information
CFN98942 Hedychenone

Hedychenone has anti-inflammatory activity, it also shows potent in vitro cytotoxic activity against cancerous cells.
CFN98956 9,9'-Di-O-(E)-feruloylsecoisolariciresinol

1,4-O-Diferuloylsecoisolariciresinol(9,9'-Di-O-(E)-feruloylsecoisolariciresinol),and pierreione B, two novel inhibitors of mTOR signaling, have strong anticancer activity. (+)-9,9′-O-Diferuloylsecoisolariciresinol has significant cytotoxic activity against the DU145, LNCaP, and A549 cell lines.
CFN98963 Boehmenan

(±)-Boehmenan shows potent protein-tyrosine phosphatase 1B (PTP1B) inhibitory activity in vitro with the IC(50) values of 43.5 uM, it inhibits PTP1B activity in a competitive manner. Boehmenan exhibits the potent cytotoxic effects against many cancer cell lines, boehmenan-mediated anti-tumor property is mediated by modulation of mitochondria and EGFR signaling pathway in A549 NSCLC cells.
CFN98969 Carpachromene

Carpachromene could be a potential anti-inflammatory agent, it blocks protein expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) in LPS-stimulated macrophages.Carpachromene shows significant α-glucosidase inhibitory activity. It also exhibits significant cytotoxicity against HepG2, PLC/PRF/5 and Raji cancer cell lines in vitro.
CFN98975 Norcepharadione B

Norcepharadione B shows good inhibitory activity against the replication of HSV-1, it also shows antimalarial activity with EC50 values of 7.5mug/ml. Norcepharadione B exhibits significant cytotoxicity against five human tumor cell lines (A-549, SK-OV-3, SK-MEL-2, XF-498 and HCT-15) in vitro. Norcepharadione B shows significant inhibitory effects on both ADP-induced and thrombin-induced platelet aggregation.