Natural Products
Momordicine I
| Catalog No. | CFN92076 |  |
| CAS No. | 91590-76-0 | |
| Molecular Weight: | 472.7 | |
| Molecular Formula | C30H48O4 | |
| DBs | [PubChem]:274954316 [ChEMBL]: [PCIDB]:34061 |
Standard InChI:
InChI=1S/C30H48O4/c1-18(2)14-20(32)15-19(3)21-10-11-29(7)26-24(33)16-23-22(8-9-25(34)27(23,4)5)30(26,17-31)13-12-28(21,29)6/h14,16-17,19-22,24-26,32-34H,8-13,15H2,1-7H3/t19-,20?,21-,22-,24+,25+,26+,28-,29+,30-/m1/s1
Biological Activity
Momordicin I has been isolated from dichloromethane extract of leaves Momordica charantia, L, the isolation was done by fractionation the dichloromethane extract followed by bioassay using artemia salina,L larvae. [1]
Momordicin I inhibits the population growth and fecundity of O. furnacalis, and its inhibition on the activities of trehalase, alkaline and acid phosphatase of larvae may be a major mechanism of action. [2]
Momordicin I and II have significant damage to the cytomembrane, can inhibit SL-1 cells growth, the mode of action by which momordicins inhibit insect cell growth and development may be useful in the development of novel pest control formulations containing cucurbitane-type triterpene glycosides. [3]
Product
References
[1] Puspawati N. J Chem, 2012,2(1): 53-6.
[2] Cao X, Zhu C Y, Zhang M X, et al. Acta Entomol Sin, 2015,58(6):625-33.
[3] Liu H, Wang G C, Zhang M X, et al. Pestic Biochem Phys, 2014, 122:110-8.
Product Use Citation
