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    Natural Products
    6''-O-Acetylglycitin
    Information
    CAS No. 134859-96-4 Price
    Catalog No.CFN93455Purity>=98%
    Molecular Weight488.44Type of CompoundFlavonoids
    FormulaC24H24O11Physical DescriptionPowder
    Download Manual    COA    MSDSSimilar structuralComparison (Web)
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    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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  • Biological Activity
    Description: 6''-O-Acetylglycitin is a potential nutriceutical, it is also a potent LDH inhibitor.
    Targets: LDH
    In vitro:
    Journal of Functional Foods, 2017, 31:295-303.
    Extraction and isolation of potential anti-stroke compounds from black soybean (Glycine max L. Merrill) guided by in vitro PC12 cell model.[Reference: WebLink]

    METHODS AND RESULTS:
    A simple and efficient method based on ultrafiltration liquid chromatography–mass spectrometry was applied to rapidly screen and identify ligands for lactate dehydrogenase (LDH) from the extracts of black soybeans (Glycine max L. Merrill), and the compounds were further assessed for ant-stroke activity using a PC12 cell model. Six major isoflavones including daidzin, glycitin, genistin, 6″-O-acetyldaidzin, 6''-O-Acetylglycitin and malonyl genistin were identified as potent LDH inhibitors. A continuous online method consisted of a microwave-assisted extraction, online solvent concentration tank and countercurrent chromatography (MAE-SCT-CCC) was newly developed for scaled up production of these compounds with high purity and efficiency.
    CONCLUSIONS:
    This novel approach using ultrafiltration LC–MS coupled with MAE-SCT-CCC and a PC12 cell model, provides not only a powerful tool for screening, extracting, and separating lactate dehydrogenase inhibitors from complex samples, but also a useful platform for large scale production of functional food and nutraceutical ingredients.
    6''-O-Acetylglycitin Description
    Source: The seeds of Glycine max
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.0473 mL 10.2367 mL 20.4733 mL 40.9467 mL 51.1834 mL
    5 mM 0.4095 mL 2.0473 mL 4.0947 mL 8.1893 mL 10.2367 mL
    10 mM 0.2047 mL 1.0237 mL 2.0473 mL 4.0947 mL 5.1183 mL
    50 mM 0.0409 mL 0.2047 mL 0.4095 mL 0.8189 mL 1.0237 mL
    100 mM 0.0205 mL 0.1024 mL 0.2047 mL 0.4095 mL 0.5118 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.