• ChemFaces is a professional high-purity natural products manufacturer.
  • Product Intended Use
  • 1. Reference standards
  • 2. Pharmacological research
  • 3. Inhibitors
  • Home
  • Natural Products
  • Bioactive
  • Screening Libraries
  • Hot Products
  • Plant Catalog
  • Customer Support
  • Product Use Citation
  • About Us
  • Contact Us
  • Natural Products
    Buddlejasaponin IVb
    Information
    CAS No. 152580-79-5 Price $118 / 20mg
    Catalog No.CFN90709Purity>=98%
    Molecular Weight943.12Type of CompoundTriterpenoids
    FormulaC48H78O18Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)
    How to Order
    Orders via your E-mail:

    1. Product number / Name / CAS No.
    2. Delivery address
    3. Ordering/billing address
    4. Contact information
    Sent to Email: info@chemfaces.com
    Contact Us
    Order & Inquiry & Tech Support

    Tel: (0086)-27-84237683
    Fax: (0086)-27-84254680
    E-mail: manager@chemfaces.com
    Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
    Delivery time
    Delivery & Payment method

    1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

    2. We accept: Wire transfer & Credit card & Paypal & Western Union
    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    Our products had been exported to the following research institutions and universities, And still growing.
  • Anna University (India)
  • Cancer Research Initatives Found... (Malaysia)
  • Florida International University (USA)
  • VIT University (India)
  • Uniwersytet Jagielloński w Krak... (Poland)
  • Fraunhofer-Institut für Molekul... (Germany)
  • University of Helsinki (Finland)
  • Institute of Bioorganic Chemistr... (Poland)
  • Leibniz Institute of Plant Bioch... (Germany)
  • The Australian National University (Australia)
  • Almansora University (Egypt)
  • More...
  • Package
    Featured Products
    Moracin M

    Catalog No: CFN92327
    CAS No: 56317-21-6
    Price: $418/5mg
    Dictamnine

    Catalog No: CFN99783
    CAS No: 484-29-7
    Price: $178/20mg
    Acteoside

    Catalog No: CFN97048
    CAS No: 61276-17-3
    Price: $60/20mg
    Przewalskin

    Catalog No: CFN99306
    CAS No: 119400-87-2
    Price: $398/5mg
    Chlorogenic acid

    Catalog No: CFN99116
    CAS No: 327-97-9
    Price: $30/20mg
    Biological Activity
    Description: Buddlejasaponin IVb(200 uM) can shorten thrombin time (TT) by 20.6 %, suggests that it has hemostasis efficacy.
    Targets: PAFR
    In vitro:
    Nat Prod Res. 2016;30(9):1001-8.
    A new triterpenoid saponin from Clinopodium chinense (Benth.) O. Kuntze.[Pubmed: 26511166 ]
    A new triterpene saponin, 3β,16β,23α,28β,30β-pentahydroxyl-olean-11,13(18)-dien-3β-yl-[β-D-glucopyranosyl-(1→2)]-[β-D-glucopyranosyl-(1→3)]-β-D-fucopyranoside, was named Clinoposaponin D (1), together with six known triterpene saponins, Buddlejasaponin IVb (2), buddlejasaponin IVa (3), buddlejasaponin IV (4), clinopodisides D (5), 11α,16β,23,28-Tetrahydroxyolean-12-en-3β-yl-[β-D-glucopyranosyl-(1→2)]-[β-D-glucopyranosyl-(1→3)]-β-D-fucopyranoside (6) and prosaikogenin A (7), and two known triterpenes, saikogenin A (8) and saikogenin F (9) were isolated from Clinopodium chinense (Benth.) O. Kuntze.
    METHODS AND RESULTS:
    Their structures were elucidated on the basis of 1D, 2D NMR and MS analysis. Meanwhile, the effects of all compounds on rabbit platelet aggregation and thrombin time (TT) were investigated in vitro. Compounds 4 and 7 had significant promoting effects on platelet aggregation with EC50 value at 53.4 and 12.2 μM, respectively. In addition, the highest concentration (200 μM) of compounds 2 and 9 shortened TT by 20.6 and 25.1%, respectively.
    Buddlejasaponin IVb Description
    Source: The herbs of Clinopodium chinense.
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
    Recent ChemFaces New Products and Compounds
    Arjunic acid

    Catalog No: CFN98397
    CAS No: 31298-06-3
    Price: $413/5mg
    Bisabolangelone

    Catalog No: CFN91876
    CAS No: 30557-81-4
    Price: $413/5mg
    Vicenin -3

    Catalog No: CFN92032
    CAS No: 59914-91-9
    Price: $218/10mg
    Pachymic acid

    Catalog No: CFN99590
    CAS No: 29070-92-6
    Price: $268/20mg
    Militarine

    Catalog No: CFN90409
    CAS No: 58139-23-4
    Price: $188/10mg
    Polyporenic acid C

    Catalog No: CFN92739
    CAS No: 465-18-9
    Price: $333/5mg
    6''-O-acetylsaikosaponin A

    Catalog No: CFN95086
    CAS No: 64340-46-1
    Price: $268/10mg
    Chrysin 6-C-glucoside 8-C-arabinos...

    Catalog No: CFN92285
    CAS No: 185145-34-0
    Price: $368/5mg
    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.

    PMID: 29328914

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.

    PMID: 29149595

    Scientific Reports 2017 Dec 11;7(1):17332.
    doi: 10.1038/s41598-017-17427-6.

    PMID: 29230013

    Molecules. 2017 Oct 27;22(11). pii: E1829.
    doi: 10.3390/molecules22111829.

    PMID: 29077044

    J Cell Biochem. 2018 Feb;119(2):2231-2239.
    doi: 10.1002/jcb.26385.

    PMID: 28857247

    Phytomedicine. 2018 Feb 1;40:37-47.
    doi:10.1016/j.phymed.2017.12.030

    PMID: 29496173
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.0603 mL 5.3016 mL 10.6031 mL 21.2062 mL 26.5078 mL
    5 mM 0.2121 mL 1.0603 mL 2.1206 mL 4.2412 mL 5.3016 mL
    10 mM 0.106 mL 0.5302 mL 1.0603 mL 2.1206 mL 2.6508 mL
    50 mM 0.0212 mL 0.106 mL 0.2121 mL 0.4241 mL 0.5302 mL
    100 mM 0.0106 mL 0.053 mL 0.106 mL 0.2121 mL 0.2651 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.