|Source:||The flowerbud of Lonicera japonica Thunb.|
|Biological Activity or Inhibitors:||1. Cryptochlorogenic acid has antioxidant activity.
|Solvent:||Pyridine, Methanol, Ethanol, etc.|
|Storage:||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
|After receiving:||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.|
|1 mg||5 mg||10 mg||20 mg||25 mg|
|1 mM||2.8224 mL||14.1119 mL||28.2239 mL||56.4477 mL||70.5597 mL|
|5 mM||0.5645 mL||2.8224 mL||5.6448 mL||11.2895 mL||14.1119 mL|
|10 mM||0.2822 mL||1.4112 mL||2.8224 mL||5.6448 mL||7.056 mL|
|50 mM||0.0564 mL||0.2822 mL||0.5645 mL||1.129 mL||1.4112 mL|
|100 mM||0.0282 mL||0.1411 mL||0.2822 mL||0.5645 mL||0.7056 mL|
Biomed Chromatogr. 2015 Jan;29(1):68-74.
|Simultaneous determination of neochlorogenic acid, chlorogenic acid, cryptochlorogenic acid and geniposide in rat plasma by UPLC-MS/MS and its application to a pharmacokinetic study after administration of Reduning injection.[Pubmed: 24842397]|
|A simple, specific and sensitive ultra-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) method was established and validated for simultaneous determination of neochlorogenic acid, chlorogenic acid, Cryptochlorogenic acid and geniposide in rat plasma using puerarin as an internal standard (IS).|
Zhongguo Zhong Yao Za Zhi. 2010 Jul;35(13):1702-5.
|Simultaneous determination of chlorogenic acid, cryptochlorogenic acid, caffeic acid, naringin, hesperidin and linarin in xiao'erjinning oral liquid by an HPLC method.[Pubmed: 20862961]|
|OBJECTIVE: To develop a HPLC method for the simultaneous determination of chlorogenic acid, Cryptochlorogenic acid, caffeic acid, naringin, hesperidin and linarin in xiao' erjinning oral liquid.
METHOD: The chromatographic separation was achieved on a Lichrospher C18 (4.6 mm x 250 mm, 5 microm) column with a mobile phase which was composed of acetonitrile(A) and 0.4% phosphoric acid(B) for gradient elution (10:90-18:82-27:73). The flow rate was (0.8-1.1-0.8) mL x min(-1), the column temperature was 30 degrees C and the detection wavelength was set at 300 nm.
RESULT: The results showed that 6 effective components were separated well and showed good linearity. The average recoveries were between 95%-105%.
CONCLUSION: The method is proved to be rapid, accurate, credible and repeatable. It can be used for the quality control of Xiao'erjinning oral liquid.
J Agric Food Chem. 2000 Nov;48(11):5512-6.
|Identification, quantitative determination, and antioxidative activities of chlorogenic acid isomers in prune (Prunus domestica L. ).[Pubmed: 11087511]|
|Neochlorogenic acid (3-CQA) and Cryptochlorogenic acid (4-CQA), isolated from prune (Prunus domestica L.), were identified by NMR and MS analyses. In addition, the quantity of chlorogenic acid isomers in prune were measured by HPLC. These isomers, 3-CQA, 4-CQA, and chlorogenic acid (5-CQA), were contained in the ratio 78.7:18. 4:3.9, respectively. 4-CQA was identified and quantified in prune for the first time, and relatively high amounts of this isomer were characteristic. Antioxidative activities of the chlorogenic acid isomers, such as scavenging activity on superoxide anion radicals and inhibitory effect against oxidation of methyl linoleate, were also evaluated. Each isomer showed antioxidative activities which were almost the same.|