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    Durantoside I
    Durantoside I
    CAS No. 53526-67-3 Price
    Catalog No.CFN97726Purity>=98%
    Molecular Weight552.53Type of CompoundIridoids
    FormulaC26H32O13Physical DescriptionPowder
    Download Manual    COA    MSDSSimilar structuralComparison (Web)
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    Biological Activity
    Description: 1. Durantoside I has inhibitory activity on the growth of lettuce seedling.
    2. Durantoside I displays DPPH scavenging activity.
    Durantoside I Description
    Source: The herbs of Duranta repens
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.

    PMID: 29328914

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.

    PMID: 29149595

    Scientific Reports 2017 Dec 11;7(1):17332.
    doi: 10.1038/s41598-017-17427-6.

    PMID: 29230013

    Molecules. 2017 Oct 27;22(11). pii: E1829.
    doi: 10.3390/molecules22111829.

    PMID: 29077044

    J Cell Biochem. 2018 Feb;119(2):2231-2239.
    doi: 10.1002/jcb.26385.

    PMID: 28857247

    Phytomedicine. 2018 Feb 1;40:37-47.
    doi: 10.1016/j.phymed.2017.12.030.

    PMID: 29496173
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.8099 mL 9.0493 mL 18.0986 mL 36.1971 mL 45.2464 mL
    5 mM 0.362 mL 1.8099 mL 3.6197 mL 7.2394 mL 9.0493 mL
    10 mM 0.181 mL 0.9049 mL 1.8099 mL 3.6197 mL 4.5246 mL
    50 mM 0.0362 mL 0.181 mL 0.362 mL 0.7239 mL 0.9049 mL
    100 mM 0.0181 mL 0.0905 mL 0.181 mL 0.362 mL 0.4525 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Durantoside I References Information
    Citation [1]

    Phytochemistry. 1995 Jul;39(4):829-33.

    Iridoid glucosides from the leaves and stems of Duranta erecta.[Pubmed: 7626266]
    From the leaves of Duranta erecta, four new iridoid glucosides, duranterectosides A, B, C and D, were isolated along with Durantoside I and Durantoside II, lamiide, lamiidoside and verbascoside. Duranterectoside A was also isolated from the stems together with Durantoside I, II and III, and lamiidoside. The structures of the new compounds were elucidated based on the spectroscopic evidence.
    Citation [2]

    Industrial Crops & Products,2015, 76(1):653-9.

    Phytochemical and phytotoxic investigation of the flowers from Citharexylum spinosum L.[Reference: WebLink]
    The aim of this study was to assess the phytotoxic potential of flowers of Citharexylum spinosum, as well as to isolate the main bioactive compounds. Results showed that the ethyl acetate extract induced the highest reduction, showing 100% inhibition of lettuce growth at 6000 ppm. This bioactive ethyl acetate extract was subjected to bio-guided chromatographic separation yielding the acetylated form of a new iridoid glucoside, designated as spinoside (1) together with two acetylated forms (2a) and (2b) of its known analogue Durantoside I (2). Their structures were established via their acetylated derivatives by means of spectroscopic and chemical data. The most inhibitory compound on the growth of lettuce seedling was identified to be the durantoside-I tetraacetylated (2b).
    Citation [3]

    J. Pharm. Res.,2013,7(2):162-6.

    New protein glycation inhibitory free radical scavenging compound from Duranta repens L.[Reference: WebLink]
    Activity guided isolation from methanolic extract of D. repens led to the identification of five iridoids namely Caryoptoside (1), Duraterectoside A (2), Durantoside III (3), Durantoside I (4), Lamiide (7) and two lignans namely (+) 5′Methoxyisolariciresinol (5), (−)5′Methoxyisolariciresinol (6). All the compounds scavenged ABTS+ radical, Caryoptoside (1) and (+) 5′Methoxyisolariciresinol (5) being most potent ABTS+ scavenger (IC50 = 6.0 and 3.1 μg/mL respectively). Only (+) 5′Methoxyisolariciresinol (5) displayed DPPH scavenging activity (IC50 = 70.5 μg/mL). Despite being potent ABTS+ scavenges, iridoid compounds rather augmented glucose induced formation of advanced glycation end-products in bovine serum albumin protein. (+) 5′Methoxyisolariciresinol (5) displayed both, the potent ABTS+ and DPPH scavenging activity however, showed mild (10%) antiglycation activity. On the other hand, (−) isomer of lignin 5′Methoxyisolariciresinol (6) that displayed moderate ABTS+ scavenging activity (IC50 = 42.6 μg/mL) potently inhibited (45%) glucose induced glycation of bovine serum albumin (BSA) protein.