Galeopsin | CAS:76475-16-6 | Manufacturer ChemFaces

Galeopsin

ChemFaces products have been cited in many studies from excellent and top scientific journals

Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC

How to Order

Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com

Delivery time

Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal

Citing Use of our Products

More Impact Factor than five Cite...

* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.

According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

Featured Products

More...

Mogroside IIe

Catalog No: CFN92191
CAS No: 88901-38-6
Price: $218/10mg

Magnolol

Catalog No: CFN98872
CAS No: 528-43-8
Price: $30/20mg

(-)-Gallocatechin gallate

Catalog No: CFN99571
CAS No: 4233-96-9
Price: $60/20mg

Luteolin-6-C-glucoside

Catalog No: CFN98137
CAS No: 4261-42-1
Price: $128/20mg

Lariciresinol

Catalog No: CFN98324
CAS No: 27003-73-2
Price: $ /

Ginsenoside Rg2

Catalog No: CFN99968
CAS No: 52286-74-5
Price: $60/20mg

Cyanidin-3-O-arabinoside chloride

Catalog No: CFN92041
CAS No: 111613-04-8
Price: $318/10mg

14-Deoxy-11,12-didehydroandrograph...

Catalog No: CFN98666
CAS No: 42895-58-9
Price: $30/20mg

Demethylsuberosin

Catalog No: CFN96241
CAS No: 21422-04-8
Price: $188/20mg

Hesperidin

Catalog No: CFN98839
CAS No: 520-26-3
Price: $30/20mg

Description:

Galeopsin shows potential anti-inflammatory activity by inhibiting proinflammatory cytokine TNF-α, it has anti-proliferative effect on several cancer cell lines.

Targets:

TNF-α

In vitro:

Phytochem Anal. 2017 Sep;28(5):404-409.

Localisation of Two Bioactive Labdane Diterpenoids in the Peltate Glandular Trichomes of Leonurus japonicus by Laser Microdissection Coupled with UPLC-MS/MS.[Pubmed: 28485033 ]

Glandular trichomes of plants are biochemical factories that could produce, store and secrete copious pharmaceutically important natural products. The Labiatae plant Leonurus japonicus is an important traditional Chinese medicine used to treat gynecological diseases, and has abundant peltate glandular trichomes (PGTs), in which the secondary metabolites accumulated are still unknown. To study the secondary metabolites specifically accumulated in the PGTs of L. japonicus and their biological activities, and provide a new way to pinpoint bioactive natural products from plants.
METHODS AND RESULTS:
Morphology of the trichomes on L. japonicus were observed under a scanning electron microscope. The PGTs of L. japonicus were precisely collected using laser microdissection (LMD) and analysed for their secondary metabolites with ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). Targeted compounds were isolated with classical phytochemical methods, and their structures were elucidated by spectroscopic analysis. Biological activities were evaluated by in vitro assays. Two labdane diterpenoids, leoheterin (1) and Galeopsin (2), were localised in the PGTs of L. japonicus. Antithrombotic activity of 1 in anti-platelet aggregation assay induced by arachidonic acid was observed. Both compounds showed potential anti-inflammatory activity by inhibiting proinflammatory cytokine TNF-α. In addition, anti-proliferative effect of both compounds on several cancer cell lines was also detected.
CONCLUSIONS:
Two bioactive labdane diterpenoids were localised in the PGTs of L. japonicus. The findings suggested that it might be an efficient approach to explore bioactive natural products from the glandular trichomes of medicinal plants with LMD-UPLC/MS/MS.

Galeopsin Description

Source:	The aerial parts of Leonurus heterophyllus SW.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Galeopsin
Price:
CAS No.:	76475-16-6
Catalog No.:	CFN89064
Molecular Formula:	C₂₂H₃₂O₅
Molecular Weight:	376.49 g/mol
Purity:	>=98%
Type of Compound:	Diterpenoids
Physical Desc.:	Powder
Source:	The aerial parts of Leonurus heterophyllus SW.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Anti-inflammatory Compound Library Anti-proliferation Compound Library Diterpenoids Compound Library TNF-α Inhibitor Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.6561 mL	13.2806 mL	26.5611 mL	53.1223 mL	66.4028 mL
5 mM	0.5312 mL	2.6561 mL	5.3122 mL	10.6245 mL	13.2806 mL
10 mM	0.2656 mL	1.3281 mL	2.6561 mL	5.3122 mL	6.6403 mL
50 mM	0.0531 mL	0.2656 mL	0.5312 mL	1.0624 mL	1.3281 mL
100 mM	0.0266 mL	0.1328 mL	0.2656 mL	0.5312 mL	0.664 mL

CFN98942	Hedychenone	56324-54-0	298.4	C₂₀H₂₆O₂
CFN89088	11,12-Dihydro-7-hydroxyhedychenone	60149-07-7	316.44	C₂₀H₂₈O₃
CFN89151	Isoleojaponin	1840966-49-5	314.42	C₂₀H₂₆O₃
CFN89116	8-Acetoxy-15,16-epoxy-8,9-secolabda-13(16),14-diene-7,9-dione	76475-32-6	376.49	C₂₂H₃₂O₅
CFN89108	6-Dehydroxy-8-hydroxygaleopsinolone	87440-66-2	316.44	C₂₀H₂₈O₃
CFN89065	Persianone	170894-20-9	632.88	C₄₀H₅₆O₆
CFN89110	Hispanone	82462-67-7	300.44	C₂₀H₂₈O₂
CFN89123	6alpha-Hydroxyhispanone	596814-48-1	316.44	C₂₀H₂₈O₃
CFN89162	6beta-Hydroxyhispanone	170711-93-0	316.44	C₂₀H₂₈O₃
CFN89087	Leojaponin	864817-63-0	314.42	C₂₀H₂₆O₃