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  • Sculponeatin N
    • Sculponeatin N
    Sculponeatin N
    Information
    CAS No. 1169805-98-4 Price
    Catalog No.CFN99267Purity>=98%
    Molecular Weight404.6 Type of CompoundDiterpenoids
    FormulaC25H40O4Physical DescriptionPowder
    Download Manual    COA    MSDSSimilar structuralComparison (Web)
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    Description: Sculponeatin N may have protective effects on the lipid peroxidation-damaged live cells.
    Sculponeatin N Description
    Source: The herbs of Rabdosia amethystoides
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.4716 mL 12.3579 mL 24.7158 mL 49.4315 mL 61.7894 mL
    5 mM 0.4943 mL 2.4716 mL 4.9432 mL 9.8863 mL 12.3579 mL
    10 mM 0.2472 mL 1.2358 mL 2.4716 mL 4.9432 mL 6.1789 mL
    50 mM 0.0494 mL 0.2472 mL 0.4943 mL 0.9886 mL 1.2358 mL
    100 mM 0.0247 mL 0.1236 mL 0.2472 mL 0.4943 mL 0.6179 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    Chem Pharm Bull (Tokyo). 2009 May;57(5):525-7.
    New terpenoids from Isodon sculponeata.[Pubmed: 19420789]

    METHODS AND RESULTS:
    Two new ent-kaurane diterpene derivatives, Sculponeatin N (1) and sculponeatin O (2), and a new A-ring contracted oleanane triterpenoid, sculponeatic acid (5), were isolated from the plant Isodon sculponeata. Their structures were elucidated on the basis of extensive spectroscopic analysis.
    CONCLUSIONS:
    This is the first report of natural occurrence of an A-ring contracted oleanane triterpenoid.
    CFN98989ent-16beta,17-Isopropylidenedioxykaurane58493-71-3346.6 C23H38O2
    CFN99267Sculponeatin N1169805-98-4404.6 C25H40O4
    CFN99268Sculponeatin O1169806-00-1440.6 C28H40O4
    CFN96482ent-17-Hydroxykaura-9(11),15-dien-19-oic acid1588516-88-4316.44C20H28O3
    CFN97752ent-17-Hydroxykaur-15-en-19-oic acid35030-38-7318.46C20H30O3
    CFN97033ent-Kauran-17,19-dioic acid60761-79-7334.5 C20H30O4
    CFN96674Siegeskaurolic acid52645-97-3320.47C20H32O3
    CFN98424ent-16beta,17-Dihydroxy-19-kauranoic acid3301-61-9336.5 C20H32O4
    CFN95172ent-16beta,17-dihydroxy-9(11)-kauren-19-oic acid55483-24-4334.5C20H30O4
    CFN97973Pterisolic acid F1401419-90-6366.5C20H30O6
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