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    Natural Products
    Calycanthoside
    Information
    CAS No. 483-91-0 Price $218 / 10mg
    Catalog No.CFN98764Purity>=98%
    Molecular Weight384.3 Type of CompoundCoumarins
    FormulaC17H20O10Physical DescriptionPowder
    Download COA    MSDS    SDF    ManualSimilar structuralComparison (Web)  (SDF)
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    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / $120.4 / In-stock
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    Calycanthoside

    Calycanthoside
    Product Name Calycanthoside
    CAS No.: 483-91-0
    Catalog No.: CFN98764
    Molecular Formula: C17H20O10
    Molecular Weight: 384.3 g/mol
    Purity: >=98%
    Type of Compound: Coumarins
    Physical Desc.: Powder
    Targets: NO | Antifection
    Source: The herbs of Sarcandra glabra
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Price: $218 / 10mg
    Download: COA    MSDS    SDF    Manual
    Similar structural: Comparison (Web)  (SDF)
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  • Industrial Crops and Products2022, 188:115596.
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  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
  • Anti-inflammatory Compound Library
  • Antibacterial Compound Library
  • Coumarins Compound Library
  • NO Inhibitor Library
  • Antifection Inhibitor Library
  • Biological Activity
    Description: Isofraxidin-7-O-glucoside(Calycanthoside ) has the anti-inflammatory effect, it has inhibitory activity on NO production.It also shows antibacterial activity.
    Targets: NO | Antifection
    In vitro:
    China Medical Herald, 2016, 13(13):20-3.
    Anti-inflammatory constituents of Acanthopanax senticosus[Reference: WebLink]
    To study the anti-inflammatory constituents of Acanthopanax senticosus.
    METHODS AND RESULTS:
    NO production in the activated RAW 264.7 macrophages induced by LPS and IFN-γ were used to evaluate anti-inflammatory activity. The compounds were isolated by HPD 100 resin, silica gel, ODS and HPLC methods, their structures were identified by Infrared TLC method and spectral imaging spectrum technology. The extraction of A. senticosus. had inhibitory activity on NO production. Seven compounds were isolated and identified as Syringin, Isofraxidin-7-O-glucoside(Calycanthoside),, Syringaresinoldi-O-β-D-glycoside, Sesamin, Daucosterol, β-sitosterol and Vanillic acid respectively.
    CONCLUSIONS:
    The extraction of A. senticosus. has the anti-inflammatory effect, and phenylpropanoids are the anti-inflammatory constituents.
    Zhongguo Zhong Yao Za Zhi,2008,33(15):1843-6.
    Studies on chemical constituents and antibacterial activity from n-butanol extract of Sarcandra glabra[Pubmed: 19007012]
    To study the chemical constituents and the antibacterial activity from n-butanol extract of Sarcandra glabra.
    METHODS AND RESULTS:
    The compounds were isolated by Diaion HP-20, Sephadex LH-20, MCI CHP-20 and silica gel column chromatographic methods. Their structures were identified on the basis of physicochemical and spectroscopic analysis. The antibacterial effect of the compounds were measured against Staphylococcus aureus by filterpaper slice method, finally the antibacterial ring in each group was recorded after 24 hours. Seven constituents were isolated and elucidated as 5, 7, 3', 4'-tetrahydroxy-6-C-beta-D-glucopyranosylflavanone(1),kaempferol-3-O-beta-D-glucuronide (2),fraxidin (3),isofraxidin (4),isofraxidin-7-O-beta-D-glucopyranoside(Calycanthoside) (5),kaempferol (6), pinostrobin (7).
    CONCLUSIONS:
    Diameters (in mm) of antibacterial ring in the compounds 2, 5, 6 were orderly recorded as follows: 14.67 +/- 0.08, 11.14 +/- 1.06, 8.26 +/- 1.26 and the compound 4 is not effective. Compounds 1-3 and 5 were isolated from S. glabra for the first time.
    Calycanthoside Description
    Source: The herbs of Sarcandra glabra
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.6021 mL 13.0107 mL 26.0213 mL 52.0427 mL 65.0533 mL
    5 mM 0.5204 mL 2.6021 mL 5.2043 mL 10.4085 mL 13.0107 mL
    10 mM 0.2602 mL 1.3011 mL 2.6021 mL 5.2043 mL 6.5053 mL
    50 mM 0.052 mL 0.2602 mL 0.5204 mL 1.0409 mL 1.3011 mL
    100 mM 0.026 mL 0.1301 mL 0.2602 mL 0.5204 mL 0.6505 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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