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    Natural Products
    Clematomandshurica saponin B
    Clematomandshurica saponin B
    Information
    CAS No. 916649-91-7 Price $388 / 5mg
    Catalog No.CFN90904Purity>=98%
    Molecular Weight1984.10Type of CompoundTriterpenoids
    FormulaC92H142O46Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)  (SDF)
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    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / $1,188.3 / In-stock
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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    Clematomandshurica saponin B

    Clematomandshurica saponin B
    Product Name Clematomandshurica saponin B
    CAS No.: 916649-91-7
    Catalog No.: CFN90904
    Molecular Formula: C92H142O46
    Molecular Weight: 1984.10 g/mol
    Purity: >=98%
    Type of Compound: Triterpenoids
    Physical Desc.: Powder
    Targets: COX-2
    Source: The roots and rhizomes of Clematis mandshurica.
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Price: $388 / 5mg
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    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
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    Description: Clematomandshurica saponin B shows significant inhibitory activity on cyclooxygenase-2 (IC50 = 2.58 microM).
    Targets: COX-2
    Clematomandshurica saponin B Description
    Source: The roots and rhizomes of Clematis mandshurica.
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 0.504 mL 2.52 mL 5.0401 mL 10.0801 mL 12.6002 mL
    5 mM 0.1008 mL 0.504 mL 1.008 mL 2.016 mL 2.52 mL
    10 mM 0.0504 mL 0.252 mL 0.504 mL 1.008 mL 1.26 mL
    50 mM 0.0101 mL 0.0504 mL 0.1008 mL 0.2016 mL 0.252 mL
    100 mM 0.005 mL 0.0252 mL 0.0504 mL 0.1008 mL 0.126 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    J Nat Prod. 2006 Nov;69(11):1591-5.
    Triterpene saponins from clematis mandshurica.[Pubmed: 17125227 ]

    METHODS AND RESULTS:
    Four new triterpene saponins, clematomandshurica saponin A, Clematomandshurica saponin B,clematomandshurica saponin C, clematomandshurica saponin D (1-4), together with three known saponins (5-7) have been isolated from the roots and rhizomes of Clematis mandshurica. Their structures were elucidated on the basis of their spectroscopic evidence and hydrolysis.
    CONCLUSIONS:
    Clematomandshurica saponin A and Clematomandshurica saponin B showed significant inhibitory activity on cyclooxygenase-2 (IC50 = 2.66 and 2.58 microM, respectively).
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