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Dimethylwulignan A1
Dimethylwulignan A1
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Dimethylwulignan A1
Price:
CAS No.: 117404-43-0
Catalog No.: CFN92718
Molecular Formula: C22H26O5
Molecular Weight: 370.4 g/mol
Purity: >=98%
Type of Compound: Lignans
Physical Desc.: Cryst.
Source: The stems of Schisandra henryi
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Dimethylwulignan A1 is a natural product from Schisandra henryi.
In vitro:
Acta Chimica Sinica, 1988, 46(5): 483-8.
Studies on the Constituents of Schisandra Henryi Ⅴ. The Structures of Wulignan A1, A2, Epiwulignan A1 and Epischisandrone)[Reference: WebLink]

METHODS AND RESULTS:
Four new lignan compounds named wulignan A1 (4), A2(5), epiwulignan A1 (6) and epischisandrone(7), and three known lignan compounds, enshicine(1), epienshicine(2) and schisandrone(3), were isolated from the fruits of Schisandra henryi Clarke collected in the district of Yibin, Sichuan Province. In anticancer screening all the four new compounds exhibit the activity against leukemia P-388 in vitro. Wulignan A_1(4), m. p. 195—197℃, [α]_D~(140-38.9°(CHCl_3), wulignan A_2(5), m. p. 235-237℃, [α]_D~(14)-61.2°(CH_3OH), epiwulignan A_1(6), m. p. 185-187℃, [α]_D~(14)+13.1°(CHCl_3), and epischisandrone (7), m. p. 182-183.5℃, [α]_D~(14)+5.5°(CHCl_3), display the features of tetralone lignan in their UV, IR, ~1H NMR (Table 1) and MS spectra.
CONCLUSIONS:
Besides the spectral analysis and NOE measurements, the structure assignments including absolute configurations mainly rely on the chemical transformation of 5, 6 and 7 into known compound, (+)-dimethylguaiacine(6b), and of 4 into known compound, (-)-dimethylisoguaiacine(4b). In addition, the following new compounds, (+)-isootobaphenol (2a), (+)-demethyleneisootobaphenol (2b), Dimethylwulignan A1 (4a) and dimethylepiwulignan A1 (6a) were prepared during the course of the structural elucidation.
Dimethylwulignan A1 Description
Source: The stems of Schisandra henryi
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.6998 mL 13.4989 mL 26.9978 mL 53.9957 mL 67.4946 mL
5 mM 0.54 mL 2.6998 mL 5.3996 mL 10.7991 mL 13.4989 mL
10 mM 0.27 mL 1.3499 mL 2.6998 mL 5.3996 mL 6.7495 mL
50 mM 0.054 mL 0.27 mL 0.54 mL 1.0799 mL 1.3499 mL
100 mM 0.027 mL 0.135 mL 0.27 mL 0.54 mL 0.6749 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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