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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / Inquiry||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Horticulture Research2022, uhac276.Pharm Biol.2021, 59(1):134-145.Biomed Pharmacother.2022, 145:112410. Food Chem Toxicol.2020, 135:110863Journal of Molecular Liquids...2022...Nutrients2022, 14(14)2929The Malaysian journal of patholog...2019...Korean J of Crop Science2019, 452-458
Appl. Sci. 2021, 11(22), 10552Sci Rep.2018, 8:9267Food Chem.2019, 278:683-691Chemistr of plant2016, 2016021195Nutraceuticals2022, 2(3),150-161Int J Mol Sci.2022, 23(15):8687. PLoS One.2017, 12(8):e0181191J Korean Soc Food Sci Nutr...2020...
Adaptive Medicine 2020, 12(1): 4-10Oxid Med Cell Longev2019, 9056845:13Antioxidants (Basel).2021, 10(8):1300. Life Sci.2022, 311(Pt A):121157.Antioxidants (Basel).2020, 9(7):581.Sci Rep.2015, 5:13194Mol Cell.2017, 68(4):673-685
Our products had been exported to the following research institutions and universities, And still growing.
Yale University (USA)University of Vigo (Spain)Uniwersytet Jagielloński w Kra... (Poland)Guangzhou Institutes of Biomedi... (China)
Julius Kühn-Institut (Germany)Copenhagen University (Denmark)Leibniz-Institut für Pflanzenb... (Germany)National Chung Hsing University (Taiwan)
Auburn University (USA)China Medical University (Taiwan)University of Hertfordshire (United Kingdom)
Humulene epoxide II
Inquire / Order:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Evid Based Complement Alternat Med.2020, 2020:8582318.The Journal of Supercritical Fluids2021, 176:105305.Molecules.2018, 23(10):E2638Front Pharmacol.2021, 12:607403.Antimicrob Agents Chemother.2020, AAC.01921-20.Biochem Systematics and Ecology2017, 11-18Antioxidants (Basel).2020, 9(2): E119Sci Rep.2017, 7:40345Trop J Nat Prod Res.2019, 3(1):6-9CZECH MYCOLOGY2021, 73(1):1-19.
Related Screening Libraries
|| Humulene epoxide II has antimalarial activity.|
|Nat Prod Res. 2015;29(9):883-6. |
|Composition and antioxidant activity of Senecio nudicaulis Wall. ex DC. (Asteraceae): a medicinal plant growing wild in Himachal Pradesh, India.[Pubmed: 25515495]|
METHODS AND RESULTS:
The composition of essential oil isolated from Senecio nudicaulis Wall. ex DC. growing wild in Himachal Pradesh, India, was analysed, for the first time, by capillary gas chromatography (GC) and GC-mass spectrometry.
A total of 30 components representing 95.3% of the total oil were identified. The essential oil was characterised by a high content of oxygenated sesquiterpenes (54.97%) with caryophyllene oxide (24.99%) as the major component. Other significant constituents were Humulene epoxide II (21.25%), α-humulene (18.75%), β-caryophyllene (9.67%), epi-α-cadinol (2.90%), epi-α-muurolol (2.03%), β-cedrene (1.76%), longiborneol (1.76%), 1-tridecene (1.16%) and citronellol (1.13%). The oil was screened for antioxidant activity using DPPH, ABTS and nitric oxide-scavenging assay.
The oil was found to exhibit significant antioxidant activity by scavenging DPPH, ABTS and nitric oxide radicals with IC50 values of 10.61 ± 0.14 μg mL(- 1), 11.85 ± 0.28 μg mL(- 1) and 11.29 ± 0.42 μg mL(- 1), respectively.
|Molecules. 2015 May 4;20(5):7990-9. |
|Chemical Composition and Insecticidal Activity of Essential Oils from Zanthoxylum dissitum Leaves and Roots against Three Species of Storage Pests.[Pubmed: 25946557]|
|This work aimed to investigate chemical composition of essential oils obtained from Zanthoxylum dissitum leaves and roots and their insecticidal activities against several stored product pests, namely the cigarette beetle (Lasioderma serricorne), red flour beetle (Tribolium castaneum) and black carpet beetle (Attagenus piceus).
METHODS AND RESULTS:
The analysis by GC-MS of the essential oils allowed the identification of 28 and 22 components, respectively. It was found that sesquiterpenoids comprised a fairly high portion of the two essential oils, with percentages of 74.0% and 80.9% in the leaves and roots, respectively. The main constituents identified in the essential oil of Z. dissitum leaves were δ-cadinol (12.8%), caryophyllene (12.7%), β-cubebene (7.9%), 4-terpineol (7.5%) and germacrene D-4-ol (5.7%), while Humulene epoxide II (29.4%), caryophyllene oxide (24.0%), diepicedrene-1-oxide (10.7%) and Z,Z,Z-1,5,9,9-tetramethyl-1,4,7-cycloundecatriene (8.7%) were the major components in the essential oil of Z. dissitum roots.
The insecticidal activity results indicated that the essential oil of Z. dissitum roots exhibited moderate contact toxicity against three species of storage pests, L. serricorne,T. castaneum and A. piceus, with LD50 values of 13.8, 43.7 and 96.8 µg/adult, respectively.
Humulene epoxide II Description
||The rhizomes of Zingiber officinale Roscoe
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|Pharm. Biol., 2004, 42(2):94-7. |
|Chemical Constituents and Preliminary Antimalarial Activity of Humiria balsamifera.[Reference: WebLink]|
METHODS AND RESULTS:
From stems and leaves of Humiria balsamifera St. (Aubl.) Hill (Humiriaceae) were isolated 6 triterpenes [arjunolic acid, 2β,3α-dihydroxy-D:A-friedooleanane, friedelin, α- and β-amyrins and lupeol], a flavonol (quercetin), an isocoumarin (bergenin) a diterpene (phytol), and 2 phytosteroids (sitosterol and stigmasterol)]. Three sesquiterpenoids [caryophyllene oxide (0.9%), Humulene epoxide II (0.3%) and trans-isolongifolenone (0.6%)], a diterpene [phytol (29.4%)] and four aliphatic esters [methyl tetra- (0.3%), hexa- (26.6%) and octadecanoate (0.3%), and ethyl tetradecanoate (26.9%)] were identified by GC/MS. Some crude extracts, arjunolic acid and bergenin, were screened in vivo and/or in vitro for their antimalarial activities against a chloroquine resistant strain. Structures of all isolated compounds were elucidated by spectroscopic analysis, including 2D NMR experiments.
All isolates, with the exception of the isocoumarin bergenin, and identified compounds as well as antimalarial activities, are described for the first time for this species.