Methyl 6-hydroxyangolensate | CAS:22255-07-8

Methyl 6-hydroxyangolensate

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Product Name	Methyl 6-hydroxyangolensate
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CAS No.:	22255-07-8
Catalog No.:	CFN98209
Molecular Formula:	C₂₇H₃₄O₈
Molecular Weight:	486.6 g/mol
Purity:	>=98%
Type of Compound:	Triterpenoids
Physical Desc.:	Powder
Source:	The barks of Khaya grandifoliola C.D.C.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
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Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
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Description:

Methyl 6-hydroxyangolensate shows antifungal and antibacterial activities.

Targets:

Antifection

In vitro:

Phytochemistry. 2013 Dec;96:312-7.

Rings B,D-seco limonoid antifeedants from Swietenia mahogani.[Pubmed: 24034555]

METHODS AND RESULTS:
Three phragmalin-type limonoids, swietephragmin H (1), swietephragmin I (2) and 11-hydroxyswietephragmin B (3), and a mexicanolide-type limonoid 2-hydroxy-6-deacetoxyswietenine (4), together with known compounds, 6-O-acetyl-2-hydroxyswietenin (5), 2-hydroxyswietenine (6), swietemahonin G (7), Methyl 6-hydroxyangolensate (8) and 7-deacetoxy-7-oxogedunin (9) were isolated from the leaves of Swietenia mahogani (Meliaceae). Their structures were established by extensive NMR experiments in conjunction with mass spectrometry.
CONCLUSIONS:
The antifeedant activity of the isolated compounds was evaluated.

Pest Manag Sci. 2005 Feb;61(2):186-90.

Antifungal activity of limonoids from Khaya ivorensis.[Pubmed: 15619711]

Chemical investigation of the diethyl ether extract of the stem bark of Khaya ivorensis A Chev (Meliaceae) afforded ten limonoids of angolensates, ring D-opened limonoids and mexicanolides.
METHODS AND RESULTS:
The structures of the limonoids isolated were determined by comparison of their (1)H and (13)C NMR data with those reported in the literature. These compounds were evaluated for their antifungal activity against the plant pathogenic fungus Botrytis cinerea Pers. Methyl 6-hydroxyangolensate and 3,7-dideacetylkhivorin were also tested for their antifungal and antibacterial activities on several fungal and bacterial species. Methyl angolensate and 1,3,7-trideacetylkhivorin displayed the highest antifungal activity against B. cinerea, with respectively 62.8 and 64.0% mycelial growth inhibition at 1000 mg litre(-1), and 73.3 and 68.6% mycelial growth inhibition at 1500 mg litre(-1).
CONCLUSIONS:
3,7-Dideacetylkhivorin showed stronger antifungal and antibacterial activities than Methyl 6-hydroxyangolensate against all of the test fungi and bacteria except Penicillium expansum Link. This is the first report on the antifungal and antibacterial effects of these limonoids. Structure-antifungal activity relationships of the limonoids isolated are discussed.

Methyl 6-hydroxyangolensate Description

Source:	The barks of Khaya grandifoliola C.D.C.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Antibacterial Compound Library Antifungal Compound Library Triterpenoids Compound Library Antifection Inhibitor Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.0551 mL	10.2754 mL	20.5508 mL	41.1015 mL	51.3769 mL
5 mM	0.411 mL	2.0551 mL	4.1102 mL	8.2203 mL	10.2754 mL
10 mM	0.2055 mL	1.0275 mL	2.0551 mL	4.1102 mL	5.1377 mL
50 mM	0.0411 mL	0.2055 mL	0.411 mL	0.822 mL	1.0275 mL
100 mM	0.0206 mL	0.1028 mL	0.2055 mL	0.411 mL	0.5138 mL

CFN98209	Methyl 6-hydroxyangolensate	22255-07-8	486.6	C₂₇H₃₄O₈
CFN99699	Methyl 6-acetoxyangolensate	16566-88-4	528.6	C₂₉H₃₆O₉
CFN98269	6-Deoxy-9alpha-hydroxycedrodorin	247036-52-8	502.6	C₂₇H₃₄O₉
CFN99337	Khayalenoid E	1220508-29-1	526.6	C₂₉H₃₄O₉
CFN98376	Seneganolide	301530-12-1	470.5	C₂₆H₃₀O₈
CFN99023	1-O-Deacetylkhayanolide E	1007387-95-2	516.6	C₂₇H₃₂O₁₀
CFN99298	1-O-Deacetyl-2alpha-hydroxykhayanolide E	1189801-51-1	532.5	C₂₇H₃₂O₁₁
CFN96576	Swietemahalactone	1514669-21-6	514.52	C₂₇H₃₀O₁₀