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    Natural Products
    Pinoresinol dimethyl ether
    Information
    CAS No. 29106-36-3 Price $168 / 20mg
    Catalog No.CFN90879Purity>=98%
    Molecular Weight386.4Type of CompoundLignans
    FormulaC22H26O6Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)  (SDF)
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    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / $60.3 / In-stock
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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    Pinoresinol dimethyl ether

    Pinoresinol dimethyl ether
    Product Name Pinoresinol dimethyl ether
    CAS No.: 29106-36-3
    Catalog No.: CFN90879
    Molecular Formula: C22H26O6
    Molecular Weight: 386.4 g/mol
    Purity: >=98%
    Type of Compound: Lignans
    Physical Desc.: Powder
    Targets: cAMP
    Source: The flowers of Magnolia denudata
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Price: $168 / 20mg
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  • Free Radic Biol Med.2017, 112:191-199
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  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
  • Lignans Compound Library
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  • Biological Activity
    Description: Pinoresinol dimethyl ether, which could be isolated from the wood of the basal tree Humbertieae, show a variety of activities as the inhibitor of cyclic AMP phosphodiesterase.
    Targets: cAMP
    Pinoresinol dimethyl ether Description
    Source: The flowers of Magnolia denudata
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.588 mL 12.94 mL 25.8799 mL 51.7598 mL 64.6998 mL
    5 mM 0.5176 mL 2.588 mL 5.176 mL 10.352 mL 12.94 mL
    10 mM 0.2588 mL 1.294 mL 2.588 mL 5.176 mL 6.47 mL
    50 mM 0.0518 mL 0.2588 mL 0.5176 mL 1.0352 mL 1.294 mL
    100 mM 0.0259 mL 0.1294 mL 0.2588 mL 0.5176 mL 0.647 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    J Nat Prod. 1999 Aug;62(8):1119-22.
    Tryptamine derived amides and acetogenins from the seeds of Rollinia mucosa.[Pubmed: 10479316 ]

    METHODS AND RESULTS:
    Bioactivity-directed fractionation of a CHCl(3)-MeOH (1:1) extract prepared from the seeds of Rollinia mucosa led to the isolation of a mixture of eight novel tryptamine amides. Extensive HPLC allowed the isolation of the major component of the mixture, which was characterized as N-lignoceroyltryptamine (6) using a combination of spectroscopic and chemical methods. The minor amides were identified by GC-MS analysis as N-palmitoyltryptamine (1), N-stearoyltryptamine (2), N-arachidoyltryptamine (3), N-behenoyltryptamine (4), N-tricosanoyltryptamine (5), N-pentacosanoyltryptamine (7), and N-cerotoyltryptamine (8). Two lignans (Pinoresinol dimethyl ether and magnolin) and six acetogenins [membranacin (9), desacetyluvaricin (10), rolliniastatin 1, bullatacin, squamocin, and motrilin] were also isolated.
    CONCLUSIONS:
    The cytotoxicity of membranacin (9) and desacetyluvaricin (10) against six human solid tumor cell lines was determined. The absolute configuration of the former is reported.
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