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    Natural Products
    Tachioside
    Information
    CAS No. 109194-60-7 Price
    Catalog No.CFN99092Purity>=98%
    Molecular Weight302.3 Type of CompoundPhenols
    FormulaC13H18O8Physical DescriptionPowder
    Download Manual    COA    MSDS    SDFSimilar structuralComparison (Web)  (SDF)
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    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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    Tachioside

    Tachioside
    Product Name Tachioside
    CAS No.: 109194-60-7
    Catalog No.: CFN99092
    Molecular Formula: C13H18O8
    Molecular Weight: 302.3 g/mol
    Purity: >=98%
    Type of Compound: Phenols
    Physical Desc.: Powder
    Targets: NO | 伪-glucosidase
    Source: The barks of Pinus yunnanensis
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Price:
    Inquire / Order: manager@chemfaces.com
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  • Exp Parasitol.2015, 153:160-4
  • Mol Pharm.2017, 14(9):3164-3177
  • Molecules.2020, 25(7):1625.
  • LWT2020, 124:109163
  • Malaysian J of Fundamental and Applied Sciences 2018, 14(3):368-373
  • Int J Biol Macromol.2020, 169:342-351
  • Nutrients.2020, 12(11):3448.
  • Phytomedicine.2019, 59:152785
  • Phytochemistry.2017, 141:162-170
  • J Sep Sci.2020, 201901140
  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
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  • Biological Activity
    Description: Tachioside has antiobesity, antioxidant and α-glucosidase inhibitory activities, it decreases lipid content in 3T3-L1 adipocytes by inhibiting lipogenesis, shows antiobesity activities. Tachioside can inhibit nitric oxide production in lipopolysaccharides-stimulated RAW 264.7 cells with IC50 value of 12.14 μM.
    Targets: NO | α-glucosidase
    In vitro:
    Bioorg Med Chem Lett. 2014 Sep 1;24(17):4120-4.
    A new phenylpropanoid and an alkylglycoside from Piper retrofractum leaves with their antioxidant and α-glucosidase inhibitory activity.[Pubmed: 25127165]

    METHODS AND RESULTS:
    Two new compounds, piperoside (1) and isoheptanol 2(S)-O-β-D-xylopyranosyl (1→6)-O-β-D-glucopyranoside (11), along with 10 known compounds 3,4-dihydroxyallylbenzene (2), 1,2-di-O-β-D-glucopyranosyl-4-allylbenzene (3), Tachioside (4), benzyl-O-β-D-glucopyranoside (5), icariside F2 (6), dihydrovomifoliol-3'-O-β-D-glucopyranoside (7), isopropyl O-β-D-glucopyranoside (8), isopropyl primeveroside (9), n-butyl O-β-D-glucopyranoside (10), isoheptanol 2(S)-O-β-D-apiofuranosyl-(1→6)-O-β-D-glucopyranoside (12), were isolated from the leaves of Piper retrofractum. Their structures were determined from 1D-NMR, 2D-NMR, and HR-ESI-MS spectral, a modified Mosher's method, and comparisons with previous reports.
    CONCLUSIONS:
    All of the isolated compounds showed modest α-glucosidase inhibitory (4.60±1.74% to 11.97±3.30%) and antioxidant activities under the tested conditions.
    Tachioside Description
    Source: The barks of Pinus yunnanensis
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.308 mL 16.5399 mL 33.0797 mL 66.1594 mL 82.6993 mL
    5 mM 0.6616 mL 3.308 mL 6.6159 mL 13.2319 mL 16.5399 mL
    10 mM 0.3308 mL 1.654 mL 3.308 mL 6.6159 mL 8.2699 mL
    50 mM 0.0662 mL 0.3308 mL 0.6616 mL 1.3232 mL 1.654 mL
    100 mM 0.0331 mL 0.1654 mL 0.3308 mL 0.6616 mL 0.827 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    J Asian Nat Prod Res. 2014 Dec;16(12):1119-25.
    Phenolic glycosides from Glycosmis pentaphylla.[Pubmed: 25367455]

    METHODS AND RESULTS:
    Three new phenolic glycosides, named as glycopentosides A-C (1-3), along with nine known compounds were isolated from the n-BuOH extract of stems of Glycosmis pentaphylla. Their structures were determined by using spectroscopic and chemical methods.
    CONCLUSIONS:
    Bioassay showed that compound 10 (Tachioside) could inhibit nitric oxide production in lipopolysaccharides-stimulated RAW 264.7 cells with IC50 value of 12.14 μM.
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