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Natural Products
Catalog No. Information
CFN00355 Clivorine

Clivorine itself has direct toxicity on HEK293 cells, and phosphorylated JNK may play some role in counteracting the toxicity of Clivorine on HEK293 cells. It has anti-proliferative function in L-02 cells may be due to its inducing cell apoptosis with independent of p53 protein. Clivorine induces hepatotoxicity and acute liver injury, which can be protected by quercetin, trolox and epidermal growth factor via inhibiting apoptotic cell death and ameliorating oxidative stress injury.
CFN90913 Clovin

Reference standards.
CFN93122 Cnidicin

Cnidicin has anti-allergic and anti-inflammatory activity, it inhibits the degranulation of mast cell and the NO generation in RAW 264.7 cells(IC50 value, 7.5 microM). Cnidicin exhibits a significant inhibition on the proliferation of cultured human tumor cells such as A549 (non small cell lung), SK-OV-3 (ovary), SK-MEL-2 (melanoma), XF498 (central nervous system) and HCT-15 (colon) in vitro .
CFN90590 Cnidilin

Cnidilin has high BBB permeability and has pharmacokinetic potentials for the treatment of central nervous system diseases.
CFN99669 Cnidioside B methyl ester

Cnidioside B exerts little immunomodulatory effect in RAW 264.7 cells.
CFN90769 Cochinchinenin A

The combination of Cochinchinenin A, cochinchinenin B, and loureirin B is the material basis for the analgesic effect of Dragon’s Blood.
CFN98503 Cochinchinenin C

There is a synergistic interaction between loureirin A and Cochinchinenin C, and the fluorescence quenching of HSA by loureirin A (or Cochinchinenin C) is a combined quenching procedure (dynamic and static quenching).
CFN99383 Coclauril

Coclauril shows anti-Hepatitis B virus (HBV) activities, with EC50 values of 7.6 ± 0.5 ug/mL.
CFN98769 Coclaurine

(+)-R-Coclaurine and (+)-S-reticuline show negative inotropic effects, coclaurine derivatives and of paeoniflorin derivatives have neuromuscular blocking actions. D-Coclaurine has a neuroleptic-like property in blocking effects of dopaminergic stimulating agents.
CFN92693 Coelonin

Coelonin shows moderate cytotoxic activity against HepG2 cells.