Hot Products
| Catalog No. | Information |
| CFN99549 | Gastrodin Gastrodin has antioxidant, cytoprotective, anticonvulsant, and anti-inflammation activities, it may be useful in the prevention and treatment of osteoporosis. Gastrodin also has protective effect to the prevention of neurotoxicity induced by ischemic stroke, the mechanism is by improving anti-oxidant and anti-inflammation activities, inhibiting apoptosis pathway, and increasing Akt phosphorylation and Nrf2 expression. Gastrodin activates PI3-K/Akt signaling and that inhibition of this pathway reverses the inhibitory effects of gastrodin on NF-κB and MAPKs activation in H9c2 cardiomyocytes. |
| CFN90338 | Gaultherin Gaultherin has analgesic, and anti-inflammatory activities.Gaultherin lacks gastric ulcerogenic effect, because of it released salicylate in intestine slowly, not in stomach and it left the cyclooxygenase-1 unaffected, which was the source of cytoprotective prostaglandins in gastric epithelium. |
| CFN90011 | Gefitinib Gefitinib (ZD-1839) is an EGFR inhibitor for Tyr1173, Tyr992, Tyr1173 and Tyr992 in the NR6wtEGFR and NR6W cells with IC50 of 37 nM, 37nM, 26 nM and 57 nM, respectively; it can reduce both cell proliferation and tumor growth of breast cancer cells expressing EGFR and/or HER2. Chronic Gefitinib treatment promotes ROS and mitochondrial dysfunction in lung cancer cells. Antioxidants may alleviate ROS-mediated resistance. |
| CFN95566 | Geissoschizine |
| CFN89459 | Geissoschizine methyl ether Geissoschizine methyl ether is a potent serotonin ₁A receptor agonist and candidate for amelioration of aggressiveness and sociality by yokukansan, it has third-generation antipsychotic-like actions at the dopamine and serotonin receptors. Geissoschizine methyl ether is a strong acetylcholinesterase (AChE) inhibitor, it inhibited 50% of AChE activity at concentrations of 3.7 ± 0.3 ug/mL. Geissoschizine methyl ether protects neurons from oxidative toxicity by shifting energy metabolism from mitochondrial respiration to glycolysis. Geissoschizine methyl ether has vasorelaxant effect, which is composed of two different mechanisms: endothelial dependency with nitric oxide and endothelial independency with voltage-dependent Ca(2+)-channel blocking. |
| CFN89019 | Gelidoside Gelidoside is a natural product from Gentiana siphonantha. |
| CFN99001 | Gelsemine Gelsemine is a highly toxic compound and may be a glycine receptor agonist. Gelsemine has antitumor, anti-hyperlipidemic,anti-oxidative activities,it also has marked antinociception in inflammatory, neuropathic and bone cancer pains without inducing antinociceptive tolerance. |
| CFN98622 | Gelsevirine Gelsevirine has anxiolytic activity, may be via the agonist action of glycine receptor in the brain. Gelsevirine can significantly inhibit the proliferation of human carcinoma cell line SW480 and MGC80-3 in a dose-dependent manner, the 50% inhibiting concentration(IC50)of gelsevirine on SW480 cells and MGC80-3 cells are 1.41±0.06 mM and 1.22±0.11 mM respectively. |
| CFN99142 | Genipin Genipin is an excellent natural cross-linker for proteins, collagen, gelatin, and chitosan cross-linking, can be used as a regulating agent for drug delivery, as the raw material for gardenia blue pigment preparation. It is a novel chemical activator of EBV lytic cycle and a cell permeable inhibitor of uncoupling protein 2 (UCP2). Genipin has antimicrobial,antiviral, antitumor, and anti-inflammatory effects, it is used for choleretic action for liver diseases control and could be used for the treatment of periodontal disease to prevent MMPs expression in periodontal lesion. It shows an antithrombotic effect in vivo due to the suppression of platelet aggregation. |
| CFN98524 | Genipin-1-O-gentiobioside Reference standards. |
