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Natural Products
Catalog No. Information
CFN90851 Marein

Marein shows neuroprotective effect on PC12 cell damage induced by methylglyoxal, which is due to a reduction of damage to mitochondria function and activation of the AMPK signal pathway, it may be a potent compound for preventing/counteracting diabetic encephalopathy. Marein can improve insulin resistance induced by high glucose in HepG2 cells through CaMKK/AMPK/GLUT1 to promote glucose uptake, through IRS/Akt/GSK-3β to increase glycogen synthesis, and through Akt/FoxO1 to decrease gluconeogenesis. Marein shows antioxidant activity, it shows Histone deacetylase enzymes (HDACs) inhibitory activity and it also can inhibit TNFα-induced NF-κB activation.
CFN95303 Margaritene

Margaritene, isomargaritene, and fortunellin could reduce lipid content by inhibiting adipogenesis.
Antioxidants.
CFN70381 Maritimein

Reference standards.
CFN92712 Marmesin

Marmesin has hepatoprotective potential; it also has cytotoxic with a 50% lethal dose of less than 0.5 micrograms/ml, is not as mutagenic or potentially carcinogenic as are AFB1, imperatorin, or MOP with BL activation.
CFN99621 Marmin

Marmin have anti-ulcer effects, which are ascribed primarily to the maintenance of the mucosal barrier integrity and inhibition of gastric motor activity and secondarily due to the prevention of the effects of endogenous acetylcholine and histamine. It can inhibit contraction of the guinea-pig tracheal smooth muscle, especially by interfering histamine receptor, inhibiting the histamine release from mast, inhibiting intracellular Ca2+ release from the intracellular store and the Ca2+ influx through voltage-dependent Ca2+ channels. Marmin shows a cell-growth inhibitory effect against L1210 and K562 in vitro.S-trans-Marmin shows potent antibacterial, fungicidal, and algicidal properties. Marmin, skimmianine, aegeline, aurapten, zeorin, and dustanin are potential to develop as antihistamine agents, especially as histamine H1 receptor antagonists by interacting with amino acid residues, Asp107, Lys179, Lys191, Asn198, and Trp428 of histamine H1 receptor.
CFN97159 Martynoside

Martynoside is a natural selective estrogen receptor modulator, which has antioxidative, anti-muscle fatigue, anticancer and antimetastatic activities. Martynoside has the potential of antagonizing sports anaemia, the mechanism of this effect might be related to preventing RBC from free radical damage.
CFN99869 Massonianoside B

Massonianoside B shows potent antioxidant activity.
CFN98707 Masticadienolic acid

Masticadienolic acid is a specific competitive inhibitor of secreted phospholipase A2, it not only protects the active site histidine from alkylation but also inhibits the action of secreted from pancreas, synovial fluid, and bee venom. Masticadienolic acid has anti-inflammatory activity, it shows effectiveness on the mouse ear inflammation induced by repeated applications of 12-0-tetradecanoylphorbol 13-acetate and on the phospholipase A2-induced foot paw edema.
CFN98983 Matairesinol

Matairesinol has radical and superoxide scavenging activities,; it also has anti-angiogenic activity by suppressing mROS signaling , can decrease hypoxia-inducible factor-1α in hypoxic HeLa cells.Matairesinol has anti-osteoporotic activity via p38/ERK-NFATc1 signaling, but not by way of anti-resorptive action. Matairesinol could markedly benefit TRAIL-based tumor therapies, including those aimed at prostate cancer.
CFN90715 Matairesinol 4'-O-beta-gentiobioside

Matairesinol 4'-O-beta-gentiobioside is a natural product from Trachelospermum jasminoides.