Info: Read More
  • Home
  • Natural Products
  • Bioactive
  • Screening Libraries
  • Hot Products
  • Plant Catalog
  • Customer Support
  • Product Use Citation
  • About Us
  • Contact Us
  • How to Order
  • Delivery time
  • Science | Nature | Cell | View More
    Screening Libraries
    Anti-melanogenic Compound Library
    A unique collection of 73 Anti-melanogenic Compound Library for high throughput screening (HTS), high content screening (HCS) and New drug research
    Cat. Size Price Stock
    L200641mg/well * 73 CompoundsInquiry In stock
    Contact Us
    L20064100uL/well (10mM solution) * 73 CompoundsInquiry In stock
    *You can select compounds, quantities, format (dry/solid or DMSO) and plate map to meet your specific requirement.
    Contact Us
    E-mail manager@chemfaces.com
    Tel (0086)-27-8423-7683
    Shelf Life (0086)-27-84254680
    ManufacturerWuhan ChemFaces Biochemical Co., Ltd.
    Package & Storage
    Container 96 Well Format Sample
    Storage Protected from air and light, refrigerate or freeze(2-8 °)
    Shelf Life 24 months (2-8 °)
    Intended UseFor research use only. Not for human use. Not sell to patients
    Description & Advantages
    1. The products in the ChemFaces screening libraries are all from plants.
    2. The biological activities or pharmacological activities of all the ChemFaces products are derived from the databases of all over the world the latest literatures, you can according to the product manuals on our website to access the relevant literatures, hope that our informations can give some inspirations and help to your research.
    3.The collections of unique natural products, which include antioxidants, anti-inflammatory, antibacterial, anticancer, and ect. Can be used for high throughput screening (HTS) and high content screening (HCS), is to help you carry out new drug screening, the emergence of new indications and other professional tools.
    4.Structurally diverse, medicinally active, and cell permeable, NMR and HPLC validated to ensure high purity.
    5. ChemFaces offers customized bioactive screening libraries , whereby you choose the specific compounds you want in the library, the quantities, plate map, concentration, and format (dry/solid or DMSO solution).
    Natural Products
    Catalog No. Information
    CFN99311 Fupenzic acid

    Fupenzic acid shows a significant decrease in intracellular melanin content in B16-F10 cells, and in culture media melanin.
    CFN99126 Saikosaponin B2

    Saikosaponin B2 as an efficient inhibitor of early HCV entry, including neutralization of virus particles, preventing viral attachment, and inhibiting viral entry/fusion. It (5 microM) induces differentiation of B16 melanoma cells, with potentiation of expressions of melanogenesis and tyrosinase.
    CFN99458 Ergosterol peroxide glucoside

    Ergosterol peroxide exhibits anti-cancer, amoebicidal, anticomplementary, antibacterial, antiviral, anti-oxdiant, and anti-melanogenic activities. Ergosterol peroxide could as an anti-atherosclerosis agent, it exhibits hACAT-1 and Lp-PLA2 inhibitory effects, with inhibitory values of 51.6 +/- 0.9 and 51.7 +/- 1.2%, at a treatment concentration of 0.23 mM. Ergosterol peroxide has osteoclastogenesis inhibitory effect, it shows an inhibitory effect in a dose-dependent manner and an inhibition rate of up to 62% with low cytotoxicity, even at a concentration as low as 1.0 microg/mL.
    CFN99550 Arbutin

    Arbutin is a tyrosinase inhibitor with an IC50 of 1.09 mM, which has gastroprotective, whitening, anti- age, anti-oxidant , anti-inflammatory, a depigmenting effects and UVB/ UVC filter. Arbutin has mutagenicity in mammalian cells after activation by human intestinal bacteria.
    CFN99586 Mulberroside A

    Mulberroside A, the major active anti-tyrosinase compound in the root bark extract of Morus alba L. (Moraceae), is widely employed as an active ingredient in whitening cosmetics. Mulberroside A has neuroprotective, analgesic, anti-inflammatory, antiapoptotic, uricosuric, nephroprotective, hypoglycemic, and antidiabetic effects.It also can protect mice against ethanol-induced hepatic damage.
    CFN99624 Gallic acid

    Gallic acid, is a histone acetyltransferase inhibitor and a potent inhibitor of brush border sucrase and other disaccharidases, which has powerful antioxidant, anti-tumor, and anti-tyrosinase activities. It can potentially interfere with the digestive functions of the intestine. It can efficiently block neuronal cell death by downregulating the expression of cytokines and the in vivo levels of NF-κB acetylation, is a possible therapeutic approach for alleviating the inflammatory progression of Alzheimer disease.
    CFN99722 Secoisolariciresinol Diglucoside

    Secoisolariciresinol diglucoside(SDG) is a phytoestrogen, estrogens and phytoestrogen from soy have been reported to have mild hypotensive effects, and SDG is a long-acting hypotensive agent, and that the hypotensive effect is mediated through the guanylate cyclase enzyme. SDG has strong antioxidant activity, cardioprotective effects, reduces the blood levels of low-density lipoprotein cholesterol, and reduces the risk of hormone related cancer.
    CFN99731 Glabridin

    Glabridin is a GABAA receptor positive modulator promoting fatty acid oxidation and improving learning and memory, which has antioxidative,anti-inflammatory, antimalarial, estrogen receptor agonism, anti-metastasis, anti-melanogenesis and neuroprotective effects. Glabridin may possess a therapeutic effect on metabolic disorders( such as diabetes and hyperglycemia), by modulating glucose metabolism through AMPK in skeletal muscle cells.
    CFN99901 Hordenine

    Hordenine is an inhibitor of noradrenaline uptake, is also an effective inhibitor of hyperpigmentation. It can inhibit melanogenesis by suppressing cAMP production, which is involved in the expression of melanogenesis-related proteins. Hordenine also has a positive inotropic effect upon the heart, increases systolic and diastolic blood pressure, peripheral blood flow volume, inhibits gut movements.
    CFN99854 Dihydromorin

    trans-Dihydromorin is an effective hypopigmenting agent in normal skin cells, hypopigmenting agents effective in melanoma system may not be effective on normal melanocytes, indicating that a non-tumor melanocyte system is more suitable for the screening of hypopigmenting agents. Dihydromorin shows strong mushroom inhibitory activity with IC50 values lower than 50 microM, more potent than (IC50 = 71.6 microM), it may be as an antibrowning agent in food systems.