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Screening Libraries
Derris robusta
A unique collection of 22 Derris robusta for high throughput screening (HTS), high content screening (HCS) and New drug research
Cat. Size Price Stock
P205581mg/well * 22 CompoundsInquiry In stock
Contact Us
P20558100uL/well (10mM solution) * 22 CompoundsInquiry In stock
*You can select compounds, quantities, format (dry/solid or DMSO) and plate map to meet your specific requirement.
Contact Us
E-mail manager@chemfaces.com
Tel (0086)-27-8423-7683
Shelf Life (0086)-27-84254680
ManufacturerWuhan ChemFaces Biochemical Co., Ltd.
Package & Storage
Container 96 Well Format Sample
Storage Protected from air and light, refrigerate or freeze(2-8 °)
Shelf Life 24 months (2-8 °)
Intended UseFor research use only. Not for human use. Not sell to patients
Description & Advantages
1. The products in the ChemFaces screening libraries are all from plants.
2. The biological activities or pharmacological activities of all the ChemFaces products are derived from the databases of all over the world the latest literatures, you can according to the product manuals on our website to access the relevant literatures, hope that our informations can give some inspirations and help to your research.
3.The collections of unique natural products, which include antioxidants, anti-inflammatory, antibacterial, anticancer, and ect. Can be used for high throughput screening (HTS) and high content screening (HCS), is to help you carry out new drug screening, the emergence of new indications and other professional tools.
4.Structurally diverse, medicinally active, and cell permeable, NMR and HPLC validated to ensure high purity.
5. ChemFaces offers customized bioactive screening libraries , whereby you choose the specific compounds you want in the library, the quantities, plate map, concentration, and format (dry/solid or DMSO solution).
Natural Products
Catalog No. Information
CFN97996 11-Hydroxytephrosin

11-Hydroxytephrosin inhibits NF-kappaB activity.
CFN97934 Deguelin

Deguelin, acts as a chemopreventive agent by blocking multiple pathways like PI3K-Akt, IKK-NF-κB, and MAPK-mTOR-survivin-mediated apoptosis. Deguelin binding to Hsp90 leads to a decreased expression of numerous oncogenic proteins, including MEK1/2, Akt, HIF1α, COX-2, and NF-κB.
Deguelin is a potent in vitro inhibitor of the mutant form of NPM1, which provides the molecular basis for its anti-leukemia activities in NPM1 mutant acute myeloid leukemia cells.Deguelin has anti-cancer activity, such as anti osteosarcoma, lung cancer; via inducing the apoptosis of cancer cells through a ROS driven Akt pathway, EPC suppression by FAK-integrin-ILK-dependent actin remodeling .Deguelin possesses antitumor effect by targeting Akt in dual axis such as EGFR and IGF1R signaling pathways and suggests that it provides an applicable therapeutic strategy for HNSCC patients.
CFN97933 12-Deoxo-12alpha-acetoxyelliptone

12-Deoxo-12alpha-acetoxyelliptone is a natural product from Derris robusta.
CFN97918 Furowanin A

Furowanin A shows significant cytotoxicity against HL-60 cells, it induces that Caspase-9 and caspase-3 inhibitors suppresses apoptosis.
CFN97917 Osajin

Osajin shows antitumor activity in different tumor cell lines, it induces apoptosis in human NPC cells through multiple apoptotic pathways, including the extrinsic death receptor pathway, and intrinsic pathways relying on mitochondria and endoplasmic reticulum stress. The cardioprotection provided by Osajin treatment results from the suppression of oxidative stress and correlates with the improved ventricular function.
CFN97906 Dehydrodeguelin

Standard reference
CFN97898 Lasiodiplodin

Lasiodiplodin may have potential anti-inflammatory activity, it shows moderate suppression effects on induced NO production. Lasiodiplodin inhibits electron transport chain.
CFN97894 Isochandalone

Isochandalone is a natural product from Derris robusta.
CFN97864 Tephrosin

Tephrosin has potent antitumor activity by inducing autophagy pathway, internalization and degradation of inactivated EGFR and ErbB2. It may be valuable for augmenting the therapeutic efficacy of 2-Deoxy-D-glucose(DG), DG is currently under clinical evaluation for targeting tumor cells.
CFN96186 3'-Methoxydaidzein

3'-Methoxydaidzein has antioxidant activity, it and geraldol have antiplatelet aggregation activity and appear to be specific against collagen‐induce platelet aggregation with a IC50 values of12.3 and 61.5 uM, respectively.