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    Screening Libraries
    Genotoxicity Compound Library
    A unique collection of 21 Genotoxicity Compound Library for high throughput screening (HTS), high content screening (HCS) and New drug research
    Cat. Size Price Stock
    L202891mg/well * 21 CompoundsInquiry In stock
    Contact Us
    L20289100uL/well (10mM solution) * 21 CompoundsInquiry In stock
    *You can select compounds, quantities, format (dry/solid or DMSO) and plate map to meet your specific requirement.
    Contact Us
    E-mail manager@chemfaces.com
    Tel (0086)-27-8423-7683
    Shelf Life (0086)-27-84254680
    ManufacturerWuhan ChemFaces Biochemical Co., Ltd.
    Package & Storage
    Container 96 Well Format Sample
    Storage Protected from air and light, refrigerate or freeze(2-8 °)
    Shelf Life 24 months (2-8 °)
    Intended UseFor research use only. Not for human use. Not sell to patients
    Description & Advantages
    1. The products in the ChemFaces screening libraries are all from plants.
    2. The biological activities or pharmacological activities of all the ChemFaces products are derived from the databases of all over the world the latest literatures, you can according to the product manuals on our website to access the relevant literatures, hope that our informations can give some inspirations and help to your research.
    3.The collections of unique natural products, which include antioxidants, anti-inflammatory, antibacterial, anticancer, and ect. Can be used for high throughput screening (HTS) and high content screening (HCS), is to help you carry out new drug screening, the emergence of new indications and other professional tools.
    4.Structurally diverse, medicinally active, and cell permeable, NMR and HPLC validated to ensure high purity.
    5. ChemFaces offers customized bioactive screening libraries , whereby you choose the specific compounds you want in the library, the quantities, plate map, concentration, and format (dry/solid or DMSO solution).
    Natural Products
    Catalog No. Information
    CFN99783 Dictamnine

    Dictamnine shows anticholinesterase, anti-inflammatory, mutagenic, and has antimicrobial activity against bacteria and fungi. It has the ability to exert cytotoxicity in human cervix, colon, and oral carcinoma cells, it at higher concentrations(≥100uM) has potential hepatotoxicity because of the cell membrane damage and mitochondrial membrane damage.
    CFN90060 Tartrazine

    Tartrazine is a food additive that belongs to a class of artificial dyes and contains an azo group; it has significant genotoxic effect , may be harmful to health and its prolonged use could trigger carcinogenesis.
    CFN90065 Sunset yellow

    Sunset yellow FCF and Brilliant Blue FCF are used as colorant food additives in many food products, they can have cytotoxic and genotoxic potential, it care must be taken when using these materials as a food additive.
    CFN98809 Verminoside

    Verminoside exhibits anti-inflammatory, anti-bacterial and anti-properties, it attenuates intracellular ROS and stress (oxidative and thermal) level promoting longevity, the longevity and stress modulation can be attributed to VMS-mediated alterations in daf-16 expression which regulates insulin signaling pathway. Verminoside induces genotoxicity on human lymphocytes, involved with PARP-1 and p53 proteins.
    CFN98866 Tryptophol

    Tryptophol is an aromatic alcohol found as a secondary product of alcoholic fermentation that induces sleep in humans. Tryptophol can inhibit the infection/replication of GVE2 by interacting with the host's Clp protease. Tryptophol can inhibit the proliferation of U937 cells by inducing apoptosis via a pathway involving caspase-8 followed by caspase-3. Tryptophol induces apoptosis through Death Receptor (DR) 5 and that the resistance of peripheral blood lymphocytes (PBL) to tryptophol-induced apoptosis might be due to competition from decoy receptor (DcR).
    CFN98883 2,6-Dimethoxy-1,4-benzoquinone

    2,6-Dimethoxy-1,4-benzoquinone exhibits strong antibacterial activities against S. pyogenes, S. mitis, and S. mutans with MIC values of 7.8, 7.8, and 15.6 ug/mL, and MBC values of 7.8, 7.8, and 31.2  ug/mL, respectively. 2,6-Dimethoxy-1,4-benzoquinone can produce genotoxic effects in patients taking dimethophrine.
    CFN00379 Ligularizine

    Ligularizine, ligularidine, and neoligularidine are possibly genotoxic carcinogens.
    CFN00408 Isatidine

    Isatidine and sceleratine slightly raise blood pressure in cats following intravenous injection, and stimulate isolated guinea pigs' uteri. Isatidine shows in vitro genotoxicity in Hep G2/SCGE assays.
    CFN00419 Integerrimine

    Prenatal exposure to Integerrimine N-oxide induces maternal toxicity, impairment of maternal care and delayed in physical and behavioral development of the offspring. Doses of Integerrimine N-oxide here employed did not produce marked immunotoxic effects.
    CFN00421 Riddelline

    Riddelline is a potent genotoxic agent in vitro and induces significant elevations in unscheduled DNA synthesis and S-phase synthesis in rat liver.