Screening Libraries
| Cat. | Size | Price | Stock | |
| L20290 | 1mg/well * 5 Compounds | Inquiry | In stock | Contact Us |
| L20290 | 100uL/well (10mM solution) * 5 Compounds | Inquiry | In stock |
| manager@chemfaces.com | |
| Tel | (0086)-27-8423-7683 |
| Shelf Life | (0086)-27-84254680 |
| Manufacturer | Wuhan ChemFaces Biochemical Co., Ltd. |
| Container | 96 Well Format Sample |
| Storage | Protected from air and light, refrigerate or freeze(2-8 °) |
| Shelf Life | 24 months (2-8 °) |
| Intended Use | For research use only. Not for human use. Not sell to patients |
| 1. The products in the ChemFaces screening libraries are all from plants. |
| 2. The biological activities or pharmacological activities of all the ChemFaces products are derived from the databases of all over the world the latest literatures, you can according to the product manuals on our website to access the relevant literatures, hope that our informations can give some inspirations and help to your research. |
| 3.The collections of unique natural products, which include antioxidants, anti-inflammatory, antibacterial, anticancer, and ect. Can be used for high throughput screening (HTS) and high content screening (HCS), is to help you carry out new drug screening, the emergence of new indications and other professional tools. |
| 4.Structurally diverse, medicinally active, and cell permeable, NMR and HPLC validated to ensure high purity. |
| 5. ChemFaces offers customized bioactive screening libraries , whereby you choose the specific compounds you want in the library, the quantities, plate map, concentration, and format (dry/solid or DMSO solution). |
| Catalog No. | Information |
| CFN98577 | Benzoylaconine Benzoylaconine and aconitine can induce reproductive toxicity in BeWo Cell, the amino acid metabolism was the main metabolic pathway and responsible for the placental and fetal toxicity of them. |
| CFN00058 | Cathinone Cathinone is the main psychoactive constituent of the khat leaf and this alkaloid is a natural amphetamine, cathinone shares the action of amphetamine on CNS as well as its sympathomimetic effects, it induces significant behavioral changes and CNS activation in the hamster by systemic administration.Cathinone has amphetamine-like effects, it can produce increases in blood pressure and in heart rate, and these changes are concomitant with the presence of cathinone in blood plasma, it has in humans euphorigenic and psychostimulant effects. Cathinone has vasoconstrictor activity which is not due to indirect or direct sympathomimetic activity, the coronary vasoconstriction may explain the increased incidence of myocardial infarction in khat chewers, which may arise from coronary vasospasm. |
| CFN98870 | beta-Asarone beta-Asarone has neuroprotection, anti-tumor, anthelmintic, anti-inflammary, and anticoagulant effects, it can afford a beneficial inhibition on both mRNA and protein expression of Bad, Bax, and cleavage of caspases 9 in rat hippocampus following intrahippocampal injections of Abeta (1-42).beta-Asarone prevents autophagy and synaptic loss by reducing ROCK expression in SAMP8 mice. beta Asarone can cause liver and cardiac damages, it also has reproductive toxicity. |
| CFN96587 | Dehydroleucodine Dehydroleucodine has antidiarrheal, anti-inflammatory, anti-microbial, embryotoxicity, gastric cytoprotective, anti-cancer activities. Dehydroleucodine has an important inhibitory effect in cellular pathways regulating adipocyte differentiation by modulating the PPARĪ³ expression, which is known to play a pivotal role during adipogenesis. Dehydroleucodine may be attributed to interference with multiple targets on the level of transcription factors, such as NF-kappaB, and cytokines. Dehydroleucodine induces a TP73-dependent transcriptional regulation of multiple cell death target genes in human glioblastoma cells. |
| CFN96846 | Diisobutyl phthalate Diisobutyl phthalate has comparable anti-androgenic effects to di-n-butyl phthalate in fetal rat testis. Diisobutyl phthalate administered by gavage is embryotoxic and teratogenic, and affects the developing male reproductive tract, at maternal toxic doses. Diisobutyl phthalate could through blood-brain barrier after oral intake, and disordered the way of apoptosis of hippocampal cells, and morphologic change of mitochondria mybe is the main reason of changes of neuron apoptosis; it induced oxidative stress, which can decrease the activities of antioxidative enzymes and result in oxidative damage of tissues. |
