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  • Bioactive Products
    Catalog No. Information
    CFN92613 Epicurzerenone

    1. Epicurzerenone , germacrone, curdione and curzerenone can be used as chemical markers for discrimination and quality control among different groups of samples.
    CFN90627 Heterophyllin B

    1. Heterophyllin B is used as the quality control index for evaluating P. heterophylla in the Chinese Pharmacopoeia.
    2. Heterophyllin B effectively suppresses the adhesion and invasion of the human esophageal carcinoma cells by mediating the PI3K/AKT/β-catenin pathways and regulating the expression levels of adhesion- and invasion-associated genes.
    CFN90861 Continentalic acid

    1. Continentalic acid and kaurenoic acid are quality control markers in Aralia continentalis.
    2. Continentalic acid shows moderate cytotoxicity against A-549 (lung), THP-1 (leukemia) and MCF-7 (breast) cell lines.
    3. Continentalic acid exerts significant anti-inflammatory activity.
    4. Continentalic acid can efficiently induces apoptosis and is a good candidate for further evaluation as an effective chemotherapeutic agent.
    5. Continentalic acid has minimum inhibitory concentrations (MICs) of approximately 8-16 microg/mL against S. aureus, including the MSSA and MRSA standard strains.
    CFN96296 1-Methyl-2-undecylquinolin-4(1H)-one

    1. 1-Methyl-2-undecyl-4(1H)-quinolone(1-Methyl-2-undecylquinolin-4(1H)-one) shows a selective inhibition of type B MAO (MAO-B) activity with the IC(50) value of 15.3 microM using a substrate kynuramine, but does not inhibit type A MAO (MAO-A) activity.
    2. 1-Methyl-2-undecyl-4(1H)-quinolone, and dihydroevocarpine should also be served as the chemical markers together with evodiamine for the quality control of Evodia rutaecarpa (Juss.) Benth.
    3. 1-Methyl-2-undecyl-4(1H)-quinolone can mitigate high phosphate-induced human aortic valve interstitial cells (HAVICs) calcification by inhibiting phosphate cotransporter (PiT-1) gene expression.
    4. 1-Methyl-2-undecyl-4(1H)-quinolone shows moderate antiangiogenic activity against human tumor cells.