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    2-2'-(Hydroxytetracosanoylamino)-octadecane-1,3,4-triol tetraacetate
    Information
    CAS No. 340702-68-3 Price
    Catalog No.CFN98439Purity>=98%
    Molecular Weight852.3 Type of CompoundCerebrosides
    FormulaC50H93NO9Physical DescriptionPowder
    Download Manual    COA    MSDS    SDFSimilar structuralComparison (Web)
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    2-2'-(Hydroxytetracosanoylamino)-octadecane-1,3,4-triol tetraacetate Description
    Source: The herbs of Phyllanthus emblica
    Biological Activity or Inhibitors: 1. (2S,3S,4R,2′R )-2-(2′-Hydroxytetracosanoylamino) octadecane-1,3,4-triol at concentration of 100 ug/mL shows selectively inhibitory activity against phospholipase A 2 (PLA 2) secreted from Crotalus adamenteus venom, but inactive against PLA 2 of bee venom (Apis mellifcra).
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.

    PMID: 29328914

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.

    PMID: 29149595

    Scientific Reports 2017 Dec 11;7(1):17332.
    doi: 10.1038/s41598-017-17427-6.

    PMID: 29230013

    Molecules. 2017 Oct 27;22(11). pii: E1829.
    doi: 10.3390/molecules22111829.

    PMID: 29077044

    J Cell Biochem. 2018 Feb;119(2):2231-2239.
    doi: 10.1002/jcb.26385.

    PMID: 28857247

    Phytomedicine. 2018 Feb 1;40:37-47.
    doi:10.1016/j.phymed.2017.12.030

    PMID: 29496173
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.1733 mL 5.8665 mL 11.733 mL 23.4659 mL 29.3324 mL
    5 mM 0.2347 mL 1.1733 mL 2.3466 mL 4.6932 mL 5.8665 mL
    10 mM 0.1173 mL 0.5866 mL 1.1733 mL 2.3466 mL 2.9332 mL
    50 mM 0.0235 mL 0.1173 mL 0.2347 mL 0.4693 mL 0.5866 mL
    100 mM 0.0117 mL 0.0587 mL 0.1173 mL 0.2347 mL 0.2933 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    2-2'-(Hydroxytetracosanoylamino)-octadecane-1,3,4-triol tetraacetate References Information
    Citation [1]

    Chinese Journal of Organic Chemistry, 2003,23(8): 853-7.

    Chemical Constituents of the Fungus Leccinum extremiorientale[Reference: WebLink]
    Thirteen chemical constituents were isolated from the fruiting bodies of basidiomyctes Leccinum extremiorientale, and their structures were elucidated by spectral and physical-chemical data as: ergosta-7,22-dien-3β,5α,6β-triol (1), ergosterol peroxide (2), ergosterol (3), ergosta-4,6,8(14),22-tetraen-3-one (4), ergosta-5,7-dien-3β-ol (5), palmitic acid (6), (2S,3S,4R,2′R)-2-2'-(Hydroxytetracosanoylamino)-octadecane-1,3,4-triol (7), cerebroside B (8), cerebroside D (9), uracil (10), inosine (11), adeosine (12) and D-allitol (13). The NMR data of compounds 8 and 9 were completely assigned by 2D-NMR techniques, including 1H-1H COSY, HMBC and HMQC.Compounds 2, 7 and 8 at concentration of 100 μg/mL showed selectively inhibitory activity against phospholipase A 2 (PLA 2) secreted from Crotalus adamenteus venom, but inactive against PLA 2 of bee venom (Apis mellifcra). In addition, the methanol-chloroform soluble extract of this fungus also showed 67% antifeedant rate against Leucaninia separata and caused 55% mortality against Plutella xylostella after three-day application.