ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
Citing Use of our Products
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Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / $289.1 / In-stock||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
University of Limpopo2016, 1-237BMC Complement Altern Med.2016, 16:213Korean Herb. Med. Inf. 2016, 4(1):35-42Bulletin of Health Research...2016...Biochem Systematics and Ecology...2017...Research on Crops.2017, 18(3):569Cell Physiol Biochem....2017...Int J Biol Macromol.2018, 112:1093-1103
Integr Cancer Ther.2018, 17(3):832-843Biofactors.2018, 44(2):168-179Front Cell Infect Microbiol.2018, 8:292Planta Med.2018, 84(6-07):465-474J of Health Science and Alternati...2019...Nutrients.2019, 12(1):E40Int J Mol Sci.2019, 20(14):E3538Chem Biol Interact.2019, 315:108910
Srinagarind Medical Journal2019, 34(1)Pharmaceutical Chemistry Journal...2019...Planta Med.2019, 85(4):347-355Appl. Sci.2020, 10,1304Saudi Pharm J2020, 10.1016Biochem Biophys Res Commun....2020...Antioxidants (Basel).2020, 9(2):E99
Our products had been exported to the following research institutions and universities, And still growing.
Max Rubner-Institut (MRI) (Germany)The Vancouver Prostate Centre (... (Canada)University of Ioannina (Greece)Universidad de Antioquia (Colombia)
Heinrich-Heine-University Düss... (Germany)Chungnam National University (Korea)Centralised Purchases Unit (CPU... (India)Leibniz-Institut für Pflanzenb... (Germany)
Universitas islam negeri Jakarta (Indonesia)Kyushu University (Japan)National Cancer Center Research... (Japan)
Related Screening Libraries
|| 6-Acetyl-2,2-dimethylchroman-4-one and vanillin show anti-platelet aggregation activity induced by arachidonic acid in vitro. |
|Phytochemistry. 2000 Apr;53(8):833-6. |
|Anti-platelet aggregation constituents from Gynura elliptica.[Pubmed: 10820787]|
METHODS AND RESULTS:
A p-hydroxyacetophenone-like derivative, (+)-gynunone, and a chromane, together with six known compounds were isolated from the CHCl3 fraction of the roots of Gynura elliptica.
Their structures were determined by means of spectral analyses.
Among the isolates, 6-Acetyl-2,2-dimethylchroman-4-one and vanillin showed anti-platelet aggregation activity induced by arachidonic acid in vitro.
|Chem Biodivers. 2007 Dec;4(12):2835-44. |
|Studies on the cytotoxicity of miscellaneous compounds from Eupatorium betonicaeforme (D.C.) Baker (Asteraceae).[Pubmed: 18081094 ]|
METHODS AND RESULTS:
A detailed study on the cytotoxic effects of five known constituents isolated from the flowers and roots of Eupatorium betonicaeforme is reported, including 2,2-dimethyl-6-vinylchroman-4-one (1), 2-senecioyl-4-vinylphenol (2), 6-Acetyl-2,2-dimethylchroman-4-one (3), (4E)-8beta-angeloyloxy-9beta,10beta-dihydroxy-1-oxogermacra-4,11(13)-dien-12,6alpha-olide (4), and 3beta-hydroxyicosan-1,5beta-olide (5). The sesquiterpene lactone 4 exhibited the highest cytotoxicity, with IC50 values ranging from 3.9 to 9.9 microM, showing some degree of cell selectivity. The antiproliferative activity of 4 was examined towards HL-60 cells, and found to diminish cell viability in a dose-dependent manner. Moreover, at all concentrations tested, there was a decrease in the number of cells capable of incorporating 5-bromo-2'-deoxyuridine (BrdU), indicating disruption of DNA synthesis. The morphological changes induced by 4 were compatible with apoptotic cell death.
This work, thus, corroborates the anticancer potential of Eupatorium secondary metabolites.
||The herbs of Vernonia cinerea
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.