Aglinin A | CAS:246868-97-3 | Manufacturer ChemFaces

Aglinin A

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Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
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Description:

Aglinin A displays moderate cytotoxicity against all the three cancer cell lines((NCI-H187), epidermoid carcinoma (KB) and breast cancer (BC) cell lines).

In vitro:

Nat Prod Res. 2011 Oct;25(17):1621-8.

Biologically active constituents of Aglaia erythrosperma.[Pubmed: 22011221]

METHODS AND RESULTS:
From the fruits and leaves of Aglaia erythrosperma (Meliaceae), 10 chemical constituents were isolated and identified, i.e. the dammarane triterpenoids cabraleadiol (1), cabraleahydroxylactone (2), ethyl eichlerianoate (3), eichlerialactone (4), Aglinin A (5), cabralealactone (6), the aglaialactone 5,6-desmethylenedioxy-5-methoxy-aglalactone (7), the flavagline 4'-demethoxy-3',4'-methylenedioxy-methyl rocaglate (8) and two coumarins: scoparone and scopoletin.
CONCLUSIONS:
Aglinin A (5) displayed moderate cytotoxicity against all the three cancer cell lines, whereas ethyl eichlerianoate (3), cabralealactone (6) and the aglaialactone 7 were exclusively cytotoxic to NCI-H187 cell line.Compounds 1-4 and 6-8 displayed minimum inhibitory concentration in the range of 25-50 µg mL(-1).

Aglinin A Description

Source:	The leaves of Aglaia perviridis
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Aglinin A
Price:
CAS No.:	246868-97-3
Catalog No.:	CFN98268
Molecular Formula:	C₃₀H₅₀O₅
Molecular Weight:	490.7 g/mol
Purity:	>=98%
Type of Compound:	Triterpenoids
Physical Desc.:	Powder
Source:	The leaves of Aglaia perviridis
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Cytotoxic Compound Library Triterpenoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.0379 mL	10.1895 mL	20.3791 mL	40.7581 mL	50.9476 mL
5 mM	0.4076 mL	2.0379 mL	4.0758 mL	8.1516 mL	10.1895 mL
10 mM	0.2038 mL	1.019 mL	2.0379 mL	4.0758 mL	5.0948 mL
50 mM	0.0408 mL	0.2038 mL	0.4076 mL	0.8152 mL	1.019 mL
100 mM	0.0204 mL	0.1019 mL	0.2038 mL	0.4076 mL	0.5095 mL

CFN99420	Richenoic acid	134476-74-7	456.7	C₃₀H₄₈O₃
CFN98946	Eichlerianic acid	56421-13-7	474.7	C₃₀H₅₀O₄
CFN98945	Methyl eichlerianate	56421-12-6	488.8	C₃₁H₅₂O₄
CFN98077	Shoreic acid	21671-00-1	474.7	C₃₀H₅₀O₄
CFN98268	Aglinin A	246868-97-3	490.7	C₃₀H₅₀O₅