Agrocybenine | CAS:178764-92-6 | Manufacturer ChemFaces

Agrocybenine

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Description:

Standard reference

In vitro:

Phytochemistry Letters, 2017 , 19 :168-171.

Pyrrolo-isoquinoline and glycosylated pyrrolidine alkaloids from Nigella glandulifera and their anti-PTP1B activity[Reference: WebLink]

METHODS AND RESULTS:
Two new alkaloids, nigellisoquinomine (1) with a novel pyrrolo-isoquinoline skeleton, and nigellapyrrolidine (2) possessing a rare glycosylated pyrrolidine moiety, together with two known alkaloids, Agrocybenine (3) and 4,6,6-trimethyl-3,4-epoxypiperidin-2-one (4), were isolated from the seeds of Nigella glandulifera Freyn. Their structures were identified by extensive NMR and HR-ESIMS analysis.
CONCLUSIONS:
Compound 1 exhibited potent protein tyrosine phosphatase 1B (PTP1B) inhibitory activity with an IC50 value of 3.65 ± 0.08 uM.

Agrocybenine Description

Source:	The herbs of Alstonia yunnanensis
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Agrocybenine
Price:
CAS No.:	178764-92-6
Catalog No.:	CFN97881
Molecular Formula:	C₁₂H₁₈N₂O
Molecular Weight:	206.3 g/mol
Purity:	>=98%
Type of Compound:	Alkaloids
Physical Desc.:	Yellow Powder
Source:	The herbs of Alstonia yunnanensis
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Alkaloids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	4.8473 mL	24.2365 mL	48.4731 mL	96.9462 mL	121.1827 mL
5 mM	0.9695 mL	4.8473 mL	9.6946 mL	19.3892 mL	24.2365 mL
10 mM	0.4847 mL	2.4237 mL	4.8473 mL	9.6946 mL	12.1183 mL
50 mM	0.0969 mL	0.4847 mL	0.9695 mL	1.9389 mL	2.4237 mL
100 mM	0.0485 mL	0.2424 mL	0.4847 mL	0.9695 mL	1.2118 mL

CFN99919	Piperine	94-62-2	285.34	C₁₇H₁₉NO₃
CFN91467	Piperyline	25924-78-1	271.3	C₁₆H₁₇NO₃
CFN95678	Pipernonaline	88660-10-0	341.5	C₂₁H₂₇NO₃
CFN95691	Dehydropipernonaline	107584-38-3	339.4	C₂₁H₂₅NO₃
CFN95664	Methyl piperate	6190-46-1	232.2	C₁₃H₁₂O₄
CFN91121	Piperlonguminine	5950-12-9	273.3	C₁₆H₁₉NO₃
CFN91508	4,5-Dihydropiperlonguminine	23512-53-0	275.4	C₁₆H₂₁NO₃
CFN95677	Pipercide (Retrofractamide B)	54794-74-0	355.5	C₂₂H₂₉NO₃
CFN95690	Retrofractamide C	96386-33-3	329.4	C₂₀H₂₇NO₃
CFN96143	Pellitorine	18836-52-7	223.4	C₁₄H₂₅NO