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    Alnusdiol
    Alnusdiol
    Information
    CAS No. 56973-51-4 Price
    Catalog No.CFN96235Purity>=98%
    Molecular Weight314.4Type of CompoundPhenols
    FormulaC19H22O4Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)
    Citing Use of our Products
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    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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    Related Libraries
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  • Biological Activity
    Description: Alnusdiol exhibits the good scavenging activities against 2, 2-diphenyl-1-picryhydrazyl (DPPH), shows moderate anti-oxidant effects.
    In vitro:
    Natural Product Research & Development, 2014 , 26 (6) :851-5.
    Phenolic Constituents from Rhizome of Wikstroemia indica and Their Anti-tumor Activity[Reference: WebLink]
    Seventeen phenolic constituents were isolated from the rhizome of Wikstroemia indica using a combination of various chromatographic methods.
    METHODS AND RESULTS:
    Their structures were elucidated and identified as wikstromol( 1),matairesinol( 2),syringaresinol( 3),pinoresinol( 4),isolariciresinol( 5),ciwujiatone( 6),isorhamnetin-3-O-robinobioside( 7),wikstaiwanone A( 8),wikstaiwanone B( 9),kaempferol( 10),rutin( 11),daphnoretin( 12),triumbelletin( 13),Alnusdiol( 14),aloe-emodin-8-O-β-D-glucoside( 15),chlorogenic acid( 16) and p-hydroxybenzoic acid( 17) by physicochemical properties and spectral data including NMR and MS. Compounds 3-9 and 13-16 were isolated from this plant for the first time.
    CONCLUSIONS:
    The anti-tumor tests showed compounds 1-4,6-9 exhibited different activities against colon cancer cell lines SW480 and SW620,in which compound 6 showed most significant activities against the two cell lines.
    Alnusdiol Description
    Source: The barks of Alnus japonica
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
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    IF=36.216(2019)

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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.1807 mL 15.9033 mL 31.8066 mL 63.6132 mL 79.5165 mL
    5 mM 0.6361 mL 3.1807 mL 6.3613 mL 12.7226 mL 15.9033 mL
    10 mM 0.3181 mL 1.5903 mL 3.1807 mL 6.3613 mL 7.9517 mL
    50 mM 0.0636 mL 0.3181 mL 0.6361 mL 1.2723 mL 1.5903 mL
    100 mM 0.0318 mL 0.159 mL 0.3181 mL 0.6361 mL 0.7952 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    Chinese Traditional & Herbal Drugs, 2013 ,44 (19) :2650-6.
    Chemical constituents in leaves of Ostryopsis nobilis and their anti-oxidant activities[Reference: WebLink]
    To study the chemical constituents of Ostryopsis nobilis and their anti-oxidant activities.
    METHODS AND RESULTS:
    The chemical constituents were isolated and purified by various column chromatographic methods.Their structures were identified by physicochemical properties and spectral analyses. Twenty-three compounds were isolated from the 95% ethanol extract and identified as loliolide(1),maslinic acid(2),vanillic acid(3),3β-(3,4-dihydroxycinnamoyl)-erythrodiol(4),dammarenediol II 3-caffeate(5),pinoresinol(6),quercetin(7),daucosterol(8),kaempferol(9),3,5-dihydroxy-1,7-bis(4H-hydroxyphenyl) heptane(10),Alnusdiol(11),casuarinondiol(12),quercetin-3-O-α-L-arabinoside(13),isoquercetin(14),2,3-dihydroxylbenzoic acid(15),isoquercetin-6″-butyl acetate(16),isoquercetin-6″-benzoate(17),4″-trans-p-coumaroyl-kaempferol-3-O-α-L-rhamnoside(18),4″-cis-p-coumaroyl-kaempferol-3-O-α-L-rhamnoside(19),maslinic acid-28-O-β-D-glucoside(20),gallic acid(21),betulatetraol(22),and L-chiroinositol(23).
    CONCLUSIONS:
    All the compounds are isolated from the plants in this genus for the first time.Diarylheptanoid compounds and other ten monomer compounds exhibit the good scavenging activities against 2,2-diphenyl-1-picryhydrazyl(DPPH),and O.nobilis extracts show moderate anti-oxidant effects.