ChemFaces is a professional high-purity natural products manufacturer.
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2. Pharmacological research
Citing Use of our Products
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / $128.7 / In-stock||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Auburn University2015, 1-58Phytother Res.2015, 29(7):1088-96Plant Cell,Tissue & Organ Culture...2016...Molecules.2016, 21(6)Phytochem Anal.2016, 27(5):296-303J Ethnopharmacol.2017, 197:157-164Journal of Analytical Chemistry...2017...J Pharm Biomed Anal.2018, 151:32-41
Int J Mol Sci.2018, 19(9):E2825Molecules.2018, 23(9):E2121Nat Commun.2019, 10(1):2745J Chromatogr B Analyt Technol Bio...2019...Chemistry of Plant Materials....2019...J Adv Res.2019, 17:85-94Int J Mol Sci.2019, 20(9):E2244J Funct Foods2019, 54:449-456
Phytomedicine.2019, 62:152962J Pharmaceut Biomed2020, 178:112894J Ethnopharmacol.2020, 249:112381Drug Chem Toxicol.2020, 1-14. Heliyon2020, 6(6):e04337.Environ Toxicol.2020, doi: 10.1002Korea Institute of Oriental Medic...2020...
Our products had been exported to the following research institutions and universities, And still growing.
Institute of Bioorganic Chemist... (Poland)Semmelweis Unicersity (Hungary)University of Virginia (USA)FORTH-IMBB (Greece)
Shanghai University of TCM (China)Georgia Institute of Technology (USA)University of Liège (Belgium)Leibniz-Institut für Pflanzenb... (Germany)
Kamphaengphet Rajabhat University (Thailand)University of Lodz (Poland)Aveiro University (Portugal)
Related Screening Libraries
|Size /Price /Stock
||10 mM * 100 uL in DMSO / Inquiry / In-stock |
10 mM * 1 mL in DMSO / Inquiry / In-stock
||Triterpenoids Compound Library
|| Asiaticoside B has notable cytotoxicity against HepG2 and MCF-7 cancer cell lines.|
|J Nat Prod. 2006 Oct;69(10):1500-2. |
|Cytotoxic cycloartane triterpene saponins from Actaea asiatica.[Pubmed: 17067171 ]|
METHODS AND RESULTS:
Three new 9,19-cycloartane triterpene glycosides, asiaticoside A (1), Asiaticoside B (2), and 25-O-ethylcimigenol-3-O-beta-D-xylopyranoside (3), together with cimiacemoside I (4), 25-O-acetylcimigenol-3-beta-O-D-xyloside (5), and 25-anhydrocimigenol-beta-O-D-xyloside (6) were isolated from the roots/rhizomes extract of Actaea asiatica, and their structures were established by spectroscopic methods (IR, HRESIMS, and NMR).
Compounds 1-3, 5, and 6 had notable cytotoxicity against HepG2 and MCF-7 cancer cell lines.
Asiaticoside B Description
||The herbs of Centella asiatica (L.) Urban
||DMSO, Pyridine, Methanol, Ethanol, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|Pharmazie. 2003 Jun;58(6):381-4. |
|An improved HPLC method for quantitative determination of six triterpenes in Centella asiatica extracts and commercial products.[Pubmed: 12856998]|
METHODS AND RESULTS:
An improved HPLC qualitative and quantitative method of six triterpenes (asiaticoside, madecassoside, asiatic acid, madecassic acid, terminolic acid, and Asiaticoside B) in Centella asiatica (raw plant material and preparations) is described in this paper. After 50 minutes the six active triterpenes were separated and detected in the methanolic extract at a limit of 0.01 microg/ml.
The method uses a Phenomenex Aqua 5mu C18 (200 A) column as the stationary phase, a gradient mobile phase of water (0.1% TFA), acetonitrile (0.1% TFA), and methyl tert-butyl ether (0.1% TFA), and UV detection at 206 nm. The correlation coefficients for the calibration curves and the recovery rates ranged from 0.995 to 0.999 and from 98.39% to 100.02%, respectively. The qualitative and quantitative results are discussed.