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    Barpisoflavone A
    Barpisoflavone A
    Information
    CAS No. 101691-27-4 Price
    Catalog No.CFN97861Purity>=98%
    Molecular Weight300.27Type of CompoundFlavonoids
    FormulaC16H12O6Physical DescriptionYellow powder
    Download     COA    MSDSSimilar structuralComparison (Web)
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    Biological Activity
    Description: 1. Barpisoflavone A possesses moderate estrogen partial agonistic activities and moderate antioxidant activities.
    Targets: Estrogen receptor | Progestogen receptor
    Barpisoflavone A Description
    Source: The herbs of Crotalaria pallida
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.

    PMID: 29328914

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.

    PMID: 29149595

    Scientific Reports 2017 Dec 11;7(1):17332.
    doi: 10.1038/s41598-017-17427-6.

    PMID: 29230013

    Molecules. 2017 Oct 27;22(11). pii: E1829.
    doi: 10.3390/molecules22111829.

    PMID: 29077044

    J Cell Biochem. 2018 Feb;119(2):2231-2239.
    doi: 10.1002/jcb.26385.

    PMID: 28857247

    Phytomedicine. 2018 Feb 1;40:37-47.
    doi: 10.1016/j.phymed.2017.12.030.

    PMID: 29496173
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.3303 mL 16.6517 mL 33.3034 mL 66.6067 mL 83.2584 mL
    5 mM 0.6661 mL 3.3303 mL 6.6607 mL 13.3213 mL 16.6517 mL
    10 mM 0.333 mL 1.6652 mL 3.3303 mL 6.6607 mL 8.3258 mL
    50 mM 0.0666 mL 0.333 mL 0.6661 mL 1.3321 mL 1.6652 mL
    100 mM 0.0333 mL 0.1665 mL 0.333 mL 0.6661 mL 0.8326 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Barpisoflavone A References Information
    Citation [1]

    Agricultural and biological chemistry.1986 July23;50(7):1809-1819.

    New 5-O-Methylisoflavones in the Roots of Yellow Lupin : Lupinus luteus L. cv. Barpine(Organic Chemistry).[Reference: WebLink]
    In addition to 5-O-methylgenistein (1), a further investigation of the isoflavonoid constituents in roots of the yellow lupin (Lupinus luteus L. cv. Barpine) has yielded five new 5-O-methylisoflavones named Barpisoflavone A (2), 5-O-methyl-lupiwighteone (3), barpisoflavone B (4), 5-O-methylderrone (5) and barpisoflavone C (6). These isoflavones were identified by physicochemical methods involving the use of other lupin isoflavones as reference compounds.
    Citation [2]

    Biosci Biotechnol Biochem. 2016;80(4):774-8.

    Biological activities of unique isoflavones prepared from Apios americana Medik.[Pubmed: 26806328]
    Four unique isoflavone aglycones (Barpisoflavone A (1), 2'-hydroxygenistein (2), 5-methylgenistein (3), and gerontoisoflavone A (4)) whose structures were related to genistein were prepared from the tuber of Apios americana Medik. We examined the estrogen receptor and androgen receptor binding activities, estrogen agonistic activities, antioxidant activities, and α-glucosidase inhibitory activities of 1-4. The results obtained showed that 2 possessed potent and 1, 3, and 4 possessed moderate estrogen partial agonistic activities, 1 and 2 possessed moderate antioxidant activities, and 2 and 3 possessed moderate α-glucosidase inhibitory activities.