ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
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4. Contact information
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Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
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1. Usually delivery time: Next day delivery by 9:00 a.m. Order now
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
More articles cited ChemFaces products.
BMC Complement Altern Med.2017 Aug 3;FEBS Lett.2015 Jan 2;589(1):182-7. JPCJuly 12, 2017Free Radic Biol Med.2016 Jun 25;97:307-319. Cytotechnology. 2017 Apr 3.
Oncol Rep.2015 Dec 22. J. of The Korean Society of Food CultureApr.2017;Aquaculture1 Dec. 2017J Ethnopharmacol.2017 Sep 14;Industrial Crops and Products2017 Jan.
Tissue and Organ Culture (PCTOC)2016 Jun 28;Virulence.2018 Jan 1;Journal of Agricultural Science2015 Sep 15Plant J. 2017 May;
Our products had been exported to the following research institutions and universities, And still growing.
Shanghai University of TCM (China)National Chung Hsing University (Taiwan)University of Sao Paulo (Brazil)Universidad Miguel Hernández (Spain)
University of East Anglia (United Kingdom)Mahidol University (Thailand)John Innes Centre (United Kingdom)Florida International University (USA)
The Ohio State University (USA)CSIRO - Agriculture Flagship (Australia)Charles University in Prague (Czech Republic)
|| Bis-5,5-nortrachelogenin has anti-allergic activity, it inhibited NO production with IC50 value of 48.6 microM. |
|Chem Pharm Bull (Tokyo). 2005 Oct;53(10):1348-51. |
|Lignans from the roots of Wikstroemia indica and their DPPH radical scavenging and nitric oxide inhibitory activities.[Pubmed: 16205001]|
METHODS AND RESULTS:
In our investigation of in vitro anti-allergic screening of medicinal herbal extracts, the ethyl acetate extract of the root of Wikstroemia indica was observed to inhibit nitric oxide (NO) production in a lipopolysaccharide (LPS) and recombinant mouse interferon-gamma (IFN-gamma) activated murine macrophage-like cell line, RAW 264.7. Fractionation of the active extract led to the isolation of two new lignan dimer Bis-5,5-nortrachelogenin (1) and bis-5,5'-nortrachelogenin (2), and three known lignans.
Compound 1 and lirioresinol B (5) inhibited NO production with IC50 values at 48.6 and 53.5 microM, respectively. Compound 5 also showed free radical scavenging effect on 1,1-diphenyl-2-picrylhydrazil (DPPH) at IC50 values at 19.5 microM.
||The roots of Wikstroemia indica
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.PMID: 29328914
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.PMID: 29149595
Scientific Reports 2017 Dec 11;7(1):17332.doi: 10.1038/s41598-017-17427-6.PMID: 29230013
Molecules. 2017 Oct 27;22(11). pii: E1829.doi: 10.3390/molecules22111829.PMID: 29077044
J Cell Biochem. 2018 Feb;119(2):2231-2239.doi: 10.1002/jcb.26385. PMID: 28857247
Phytomedicine. 2018 Feb 1;40:37-47. doi:10.1016/j.phymed.2017.12.030PMID: 29496173
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.