ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
Citing Use of our Products
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / Inquiry||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Phytochem Anal.2016, 27(5):296-303Pharm Biol.2017, 55(1):360-366Pharmacol Rep.2017, 69(6):1224-1231Plant J.2017, 90(3):535-546Int J Mol Sci.2018, 19(9):E2601J Sep Sci.2018, 41(7):1682-1690Mol Cells.2018, 41(8):771-780Food and Fermentation Industries...2018...
Phytother Res.2019, 10.1002Mol Microbiol.2019, 112(1):317-332ACS Chem Biol.2019, 14(5):873-881Nutr Metab (Lond).2019, 16:31Evid Based Complement Alternat Me...2019...Journal of Apiculture...2019...Biochem Biophys Res Commun....2019...J Nat Prod.2019, 82(4):1002-1008
Antioxidants (Basel).2020, 9(2):E99Asian J Beauty Cosmetol...2020...BMC Complement Med Ther. ...2020...J Ethnopharmacol.2020, 260:112988.J Agric Food Chem....2020...Drug Dev Res.2020, doi: 10.1002Functional Ecology2020, doi: 10.1111.
Our products had been exported to the following research institutions and universities, And still growing.
Universiti Malaysia Pahang (Malaysia)Mahatma Gandhi University (India)University of Medicine and Phar... (Romania)Weizmann Institute of Science (Israel)
St. Jude Children Research Hosp... (USA)Tokyo Woman's Christian University (Japan)University of Minnesota (USA)Kazusa DNA Research Institute (Japan)
Pennsylvania State University (USA)MTT Agrifood Research Finland (Finland)University of Bonn (Germany)
Related Screening Libraries
|| Bis-5,5-nortrachelogenin has anti-allergic activity, it inhibited NO production with IC50 value of 48.6 microM. |
|Chem Pharm Bull (Tokyo). 2005 Oct;53(10):1348-51. |
|Lignans from the roots of Wikstroemia indica and their DPPH radical scavenging and nitric oxide inhibitory activities.[Pubmed: 16205001]|
METHODS AND RESULTS:
In our investigation of in vitro anti-allergic screening of medicinal herbal extracts, the ethyl acetate extract of the root of Wikstroemia indica was observed to inhibit nitric oxide (NO) production in a lipopolysaccharide (LPS) and recombinant mouse interferon-gamma (IFN-gamma) activated murine macrophage-like cell line, RAW 264.7. Fractionation of the active extract led to the isolation of two new lignan dimer Bis-5,5-nortrachelogenin (1) and bis-5,5'-nortrachelogenin (2), and three known lignans.
Compound 1 and lirioresinol B (5) inhibited NO production with IC50 values at 48.6 and 53.5 microM, respectively. Compound 5 also showed free radical scavenging effect on 1,1-diphenyl-2-picrylhydrazil (DPPH) at IC50 values at 19.5 microM.
||The roots of Wikstroemia indica
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.