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Callimorphine
Callimorphine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Callimorphine
Price:
CAS No.: 74991-73-4
Catalog No.: CFN00246
Molecular Formula: C15H23NO5
Molecular Weight: 297.35 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Heliotropium indicum L.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Reference standards.
In vitro:
Insect Biochemistry and Molecular Biology,2007,37(1):80–89.
Absolute configuration of the creatonotines and callimorphines, two classes of arctiid-specific pyrrolizidine alkaloids[Reference: WebLink]

METHODS AND RESULTS:
There are two classes of insect PAs, the creatonotines and the Callimorphines. The creatonotines contain as necic acids either 2-hydroxy-3-methylbutyric acid (creatonotine A) or 2-hydroxy-3-methylpentanoic acid (creatonotine B). The three known Callimorphines contain 2-hydroxy-2-methylbutanoic acid whose hydroxyl group can be either free (deacetylCallimorphine) or acetylated (Callimorphine) or propionylated (homoCallimorphine).
CONCLUSIONS:
Analysis of the creatonotines and Callimorphines isolated from the polyphagous arctiids Estigmene acrea and Grammia geneura that were fed with pure PAs and defined PA mixtures revealed the following absolute configuration: the Callimorphines and creatonotine A were present in 2′R configuration, whereas creatonotine B was found as mixture of (2′R, 3′S)- and (2′S, 3′S)-stereoisomers. The ratio of 2′S to 2′R was extremely variable ranging from 98% S to 94% R.
Callimorphine Description
Source: The herbs of Heliotropium indicum L.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.363 mL 16.8152 mL 33.6304 mL 67.2608 mL 84.076 mL
5 mM 0.6726 mL 3.363 mL 6.7261 mL 13.4522 mL 16.8152 mL
10 mM 0.3363 mL 1.6815 mL 3.363 mL 6.7261 mL 8.4076 mL
50 mM 0.0673 mL 0.3363 mL 0.6726 mL 1.3452 mL 1.6815 mL
100 mM 0.0336 mL 0.1682 mL 0.3363 mL 0.6726 mL 0.8408 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Tetrahedron Letters,1980,21(14):1383–1384.
Callimorphine: identification and synthesis of the cinnabar moth “metabolite”.[Reference: WebLink]

METHODS AND RESULTS:
Callimorphine, a putative pyrrolizidine alkaloid metabolite found in some Arctiid moths which feed as larvae on plants containing pyrrolizidine alkaloids, has been identified and synthesised.
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CAS No: 27215-14-1
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3-Hydroxy-4-methoxycinnamic acid

Catalog No: CFN99135
CAS No: 537-73-5
Price: $30/20mg
Juglone

Catalog No: CFN90497
CAS No: 481-39-0
Price: $40/20mg
Dendrobine

Catalog No: CFN99133
CAS No: 2115-91-5
Price: $188/20mg
Ginsenoside Rg5

Catalog No: CFN92643
CAS No: 186763-78-0
Price: $168/10mg
Tanshinone I

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CAS No: 568-73-0
Price: $30/20mg
Elemicin

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ar-Turmerone

Catalog No: CFN89231
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Rhaponiticin

Catalog No: CFN98569
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Price: $60/20mg
Trametenolic acid

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