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    Clerodenoside A
    Clerodenoside A
    Information
    CAS No. 164022-75-7 Price
    Catalog No.CFN99691Purity>=98%
    Molecular Weight736.7 Type of CompoundPhenylpropanoids
    FormulaC35H44O17Physical DescriptionPowder
    Download Manual    COA    MSDSSimilar structuralComparison (Web)
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    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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  • Biological Activity
    Description: Clerodenoside A has antioxidant activity.
    In vitro:
    Chinese Traditional and Herbal Drugs, 2012,43(6): 1050-6.
    Chemical constituents of Clerodendrum lindleyi and their free radical scavenging activities[Reference: WebLink]
    To study the chemical constituents from the roots and stems of Clerodendrum lindleyi and their in vitro activities of DPPH free radical scavenging.
    METHODS AND RESULTS:
    The constituents were isolated and purified by various column chromatographic techniques and their structures were identified on the basis of their physicochemical and spectral data.Free radical scavenging activity of the isolated constituents was investigated in vitro using the DPPH assay. Thirteen constituents were isolated from C.lindleyi and identified as betulinic acid(1),monoacetylmartinoside(2),4″-O-acetylmartynoside(3),Clerodenoside A(4),3″,4″-O-acetylmartynoside(5),acteoside(6),friedelin(7),glutinol(8),taraxerol(9),uncinatone(10),mandarone E(11),(24S)-24ethylcholesta-5,22,25-trien-3β-ol(12),and hedyotol C 4″-O-β-D-glucopyranoside(13).Compounds 1—6 were obtained from the roots and 7—13 were from the stems.Bioassay indicated that compounds 1—12 had different free radical scavenging activities.
    CONCLUSIONS:
    Compounds 1—13 are all obtained from C.lindleyi for the first time. Compound 13 is obtained from the plants in Clerodendrum Linn.for the first time.Phenylethanoid glycosides,diterpenoids,triterpenoids,and sterol obtained show different free radical scavenging activities.Phenylethanoid glycosides 4″-O-acetylmartynoside,monoacetylmartinoside,and acteoside exhibit the most significant activity.
    Clerodenoside A Description
    Source: The herbs of Pedicularis chinensis Maxim
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.3574 mL 6.787 mL 13.574 mL 27.1481 mL 33.9351 mL
    5 mM 0.2715 mL 1.3574 mL 2.7148 mL 5.4296 mL 6.787 mL
    10 mM 0.1357 mL 0.6787 mL 1.3574 mL 2.7148 mL 3.3935 mL
    50 mM 0.0271 mL 0.1357 mL 0.2715 mL 0.543 mL 0.6787 mL
    100 mM 0.0136 mL 0.0679 mL 0.1357 mL 0.2715 mL 0.3394 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    Nat Prod Commun. 2009 Mar;4(3):323-5.
    A new rearranged abietane diterpene and other constituents from Clerodendrum philipinum.[Pubmed: 19413107]

    METHODS AND RESULTS:
    From the methanolic extract of the roots of Clerodendrum philipinum, a new rearranged abietane diterpene (1) and eight known compounds were isolated by various chromatography methods. Their structures were identified by means of spectroscopic methods, including 1D- and 2D-NMR, as 17(15-->16),18(4-->3)-bisabeo-11,12,14,16-tetrahydroxy-3,5,8,11,13,15-abietahexaen-7-one (1), binankadsurin A, Clerodenoside A, martynoside, acteoside, isoacteoside, astragalin, p3-sitosterol, and daucosterol.
    CONCLUSIONS:
    Binankadsurin A was found for the first time from a Clerodendrum species.