ChemFaces is a professional high-purity natural products manufacturer.
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1. Reference standards
2. Pharmacological research
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More articles cited ChemFaces products.
Anal Bioanal Chem.2018 Feb;PLoS One. 2017 Mar 9;Phytomedicine2015 March 20.Journal of Functional FoodsFeb. 2018;J Ethnopharmacol.2018 Jan 10;
Semyung UniversityJan. 2017;J. of Pha. and Biomed. Analysis25 Jan. 2016Clin Exp Pharmacol Physiol.2015 Aug 1Phytomedicine.2018 Jan 1;Int J Biol Macromol. 2018 Feb 12.
Cell Physiol Biochem. 2017;44(4);J Ethnopharmacol. 2017 Jul 12;Universite de Bordeaux15 Dec 2017;Aquaculture1 Dec. 2017
Our products had been exported to the following research institutions and universities, And still growing.
University of Perugia (Italy)University of Wollongong (Australia)Medizinische Universit?t Wien (Austria)University of Pretoria (South Africa)
University of Maryland School of... (USA)Leibniz-Institut für Pflanzenbi... (Germany)Chang Gung University (Taiwan)Universidad de Ciencias y Artes ... (Mexico)
University of the Basque Country (Spain)University of Minnesota (USA)The Institute of Cancer Research (United Kingdom)
|| Complanatoside A is a flavonol glycoside isolated from Astragalus complanatus, and currently it is used as a quality control index for A. complanatus in the 2010 edition of the Chinese Pharmacopoeia.|
|Biomed Chromatogr. 2016 Jun;30(6):888-93. |
|Quantification of complanatoside A in rat plasma using LC-MS/MS and its application to a pharmacokinetic study.[Pubmed: 26393341]|
|Complanatoside A is a flavonol glycoside isolated from Astragalus complanatus, and currently it is used as a quality control index for A. complanatus in the 2010 edition of the Chinese Pharmacopoeia. |
METHODS AND RESULTS:
For the first time, a simple and sensitive LC-MS/MS method was developed for the determination of Complanatoside A in rat plasma over the range of 2.3-575 ng/mL. Complanatoside A was extracted from plasma by a protein precipitation procedure, separated by LC and detected by MS/MS in positive electrospray ionization mode. The method was validated for selectivity, carryover, sensitivity, linearity, extraction recovery, matrix effect, accuracy, precision and stability studies. The lower limit of quantification was established at 2.3 ng/mL. Intra- and inter-day precisions (LLOQ, low-QC, med-QC and high-QC) were <7.9%, and accuracies were between 94.0 and 105.1%. Matrix effect was acceptable (97.9-103.0%) and extraction recovery was reproducible (88.5-94.4%). Complanatoside A was stable in the investigated conditions.
The method was applied to the pharmacokinetics of Complanatoside A in rats.
Complanatoside A Description
||The seeds of Astragalus complanatus
||DMSO, Pyridine, Methanol, Ethanol, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.PMID: 29328914
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.PMID: 29149595
Scientific Reports 2017 Dec 11;7(1):17332.doi: 10.1038/s41598-017-17427-6.PMID: 29230013
Molecules. 2017 Oct 27;22(11). pii: E1829.doi: 10.3390/molecules22111829.PMID: 29077044
J Cell Biochem. 2018 Feb;119(2):2231-2239.doi: 10.1002/jcb.26385. PMID: 28857247
Phytomedicine. 2018 Feb 1;40:37-47. doi:10.1016/j.phymed.2017.12.030PMID: 29496173
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|Zhongguo Zhong Yao Za Zhi. 2005 Apr;30(8):600-2. |
|[Determination of complanatoside A in semen Astragali complanati by HPLC].[Pubmed: 16011285]|
To establish the determination method for Complanatoside A in seeds of Astragalus complanatus. |
METHODS AND RESULTS:
An HPLC method has been developed to separate Complanatoside A on ZORBAX EXTEND-C18 (4.6 mm x 250 mm, 5 microm) column with acetonitrile-water-phosphoric acid (20:80:0.2) as mobile phase and UV detection at 267 nm. The good linearity of Complanatoside A ranged 0.086-0.430 microg, r = 0.9999. An average recovery of 99.8% (n = 5) was obtained with a RSD of 1.0%.
METHODS AND RESULTS:
The established method is proved to be stability, fast, accurate and can be used for quantification of Complanatoside A in Semen Astragali Complanati.