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    3-O-beta-D-Glucopyranosylplatycodigenin
    3-O-beta-D-Glucopyranosylplatycodigenin
    Information
    CAS No. 38337-25-6 Price $268 / 5mg
    Catalog No.CFN90950Purity>=98%
    Molecular Weight682.85Type of CompoundTriterpenoids
    FormulaC36H58O12Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)
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    Biological Activity
    Description: 3-O-beta-D-Glucopyranosylplatycodigenin may have in vitro anti-proliferative activity against the HSC-T6 cell line.
    In vitro:
    Molecules. 2012 Dec 13;17(12):14899-907.
    Two new oleanane-type triterpenoids from Platycodi Radix and anti-proliferative activity in HSC-T6 cells.[Pubmed: 23519261 ]

    METHODS AND RESULTS:
    Two new oleanane-type triterpenoids, named platycodonoids A and B (1, 2), together with five known saponins, including platycodin D (3), deapioplatycodin D (4), 3-O-β-D-glucopyranosyl polygalacic acid (5), 3-O-beta-D-Glucopyranosylplatycodigenin (6) and polygalacin D (7), were isolated from the roots of Platycodon grandiflorum. On the basis of spectral data and chemical evidence, the structures of the new compounds were elucidated as 2β,3β,23,24-tetrahydroxy-28-nor-olean-12-en-16-one (1) and 2β,3β,23,24- tetrahydroxy-28-nor-olean-12-en-16-one-3-O-β-D-glucopyranoside (2).
    CONCLUSIONS:
    Compounds 1-7 were evaluated for their in vitro anti-proliferative activity against the HSC-T6 cell line.
    3-O-beta-D-Glucopyranosylplatycodigenin Description
    Source: The roots of Platycodon grandiflorum.
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.4645 mL 7.3223 mL 14.6445 mL 29.289 mL 36.6113 mL
    5 mM 0.2929 mL 1.4645 mL 2.9289 mL 5.8578 mL 7.3223 mL
    10 mM 0.1464 mL 0.7322 mL 1.4645 mL 2.9289 mL 3.6611 mL
    50 mM 0.0293 mL 0.1464 mL 0.2929 mL 0.5858 mL 0.7322 mL
    100 mM 0.0146 mL 0.0732 mL 0.1464 mL 0.2929 mL 0.3661 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    Zhongguo Zhong Yao Za Zhi. 2006 Sep;31(18):1506-9.
    Chemical constituents from roots of Platycodon grandiflorum.[Pubmed: 17144467]
    To study the chemical constituents from roots of Platycodon grandiflorum.
    METHODS AND RESULTS:
    Column chromatography (silica gel, macroporous resin, sephadex LH - 20 and the preparative RP - HPLC were used to isolate the constituents. Their structures were elucidated by physical and spectral data. Eight compounds were isolated and identified as tangeritin (1), 3-O-beta-D-Glucopyranosylplatycodigenin methyl ester (2), 3-O-beta-D-glucopyranosylplaticogenic acid A lactone (3), 3-O-beta-D-Glucopyranosylplatycodigenin (4), deapio-platyconic acid A lactone (5), deapio-platycodin-D (6), platycoside-G1 (7) and platycoside-E (8).
    CONCLUSIONS:
    Compounds 1,3 and 5 were isolated from this plant for the first time.