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    Coriatin
    Coriatin
    Information
    CAS No. 91653-75-7 Price
    Catalog No.CFN97480Purity>=98%
    Molecular Weight296.3 Type of CompoundSesquiterpenoids
    FormulaC15H20O6Physical DescriptionPowder
    Download Manual    COA    MSDSSimilar structuralComparison (Web)
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    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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  • Biological Activity
    Description: Coriatin and corianin demonstrate synergistic effect to insecticidal activity of tutin againstarmyworm.
    Coriatin Description
    Source: The herbs of Coriaria nepalensis Wall.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.375 mL 16.8748 mL 33.7496 mL 67.4992 mL 84.3739 mL
    5 mM 0.675 mL 3.375 mL 6.7499 mL 13.4998 mL 16.8748 mL
    10 mM 0.3375 mL 1.6875 mL 3.375 mL 6.7499 mL 8.4374 mL
    50 mM 0.0675 mL 0.3375 mL 0.675 mL 1.35 mL 1.6875 mL
    100 mM 0.0337 mL 0.1687 mL 0.3375 mL 0.675 mL 0.8437 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Animal Research:
    Journal of Northwest Forestry University, 2014, 29(1):105-10.
    The Preliminary Study on Pesticidal Activity of Main Components in Coriaria Lactone[Reference: WebLink]

    METHODS AND RESULTS:
    Toxic symptom and contact poisoning activity of tutin,Coriatin and corianin were observed on the larvae of Mythimna separata with 3,4,5and 6instars by leaf disk method and dripping method.The results showed that the poisoning symptoms for tutin included slow in action,coma,recovery,paralysis,and dehydration on body surface,but the symptoms did not appear by using Coriatin and corianin.After treated by different proportions(1∶3,1∶1,3∶1)of tutin and Coriatin,larvae with 3,4,5instars demonstrated the symptom of coma with various degrees,and the largest number of coma was 4instars,and the coma disappeared in 6instars.Different proportions of tutin and corianin caused a decreased number of coma symptom in the larvae with 3,and 4instars,and partial coma in 6instars.Direct dripping different concentrations of tuin to each instars insect demonstrated poisoning actions,concentration 1.00mg·mL-1 exhibited the strongest poisoning effect.Different ratios of tuin and Coriatin,tuin and corianin on armyworm had significant influence on appetite and cumulative mortality rates,along with the increase of Coriatin and corianin, the impact on armyworm food intake and cumulative mortality was more significant.
    CONCLUSIONS:
    It was preliminarily concluded that Coriatin and corianin demonstrated synergistic effect to insecticidal activity of tutin againstarmyworm.