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    Cyclo(Leu-Val)
    Information
    CAS No. 5625-50-3 Price $332 / 10mg
    Catalog No.CFN90291Purity>=98%
    Molecular Weight212.29Type of CompoundMiscellaneous
    FormulaC11H20N2O2Physical DescriptionSolid
    Download Manual    COA    MSDSSimilar structuralComparison (Web)
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    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / $151.1 / In-stock
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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    10 mM * 1 mL in DMSO / Inquiry / In-stock
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  • Biological Activity
    Description: Cyclo(Leu-Val) is a cyclic dipeptide from the fermentation broth of F8712 strain.
    In vitro:
    《Academic Journal of Second Military Medical University》 2006-01
    Bioactive cyclodipeptides extracted from marine microbes in East China Sea[Reference: WebLink]
    To search for bioactive compounds from marine microbes.
    METHODS AND RESULTS:
    Pyricularia oryzae was used to screen microbes.Compounds extracted with EtOAc from the fermentation broth of F8712 strain(an active microbe screened out) were separated.The chemical structures of the separated compounds were identified by ~(1)HNMR,~(13)CNMR and ESI-MS techniques. Six cyclic dipeptides,cyclo(Ala-Leu),cyclo(Ala-Ile),cyclo(Ile-Pro),cyclo(Val-Pro),cyclo(Leu-Pro) and Cyclo(Leu-Val),were obtained.
    CONCLUSIONS:
    : None of the 6 cyclodipeptides has any anti-Pyricularia oryzae activities.Compound Ⅴ has potent inhibitory effects on Vibrio anguillarm with a minimum inhibitory concentration of 0.07 μg/ml.
    Cyclo(Leu-Val) Description
    Source: The roots of Panax notoginseng (Burk.)F.H.Chen
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 4.7105 mL 23.5527 mL 47.1054 mL 94.2107 mL 117.7634 mL
    5 mM 0.9421 mL 4.7105 mL 9.4211 mL 18.8421 mL 23.5527 mL
    10 mM 0.4711 mL 2.3553 mL 4.7105 mL 9.4211 mL 11.7763 mL
    50 mM 0.0942 mL 0.4711 mL 0.9421 mL 1.8842 mL 2.3553 mL
    100 mM 0.0471 mL 0.2355 mL 0.4711 mL 0.9421 mL 1.1776 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.