• ChemFaces is a professional high-purity natural products manufacturer.
  • Product Intended Use
  • 1. Reference standards
  • 2. Pharmacological research
  • 3. Inhibitors
  • Home
  • Natural Products
  • Bioactive
  • Screening Libraries
  • Hot Products
  • Plant Catalog
  • Customer Support
  • Product Use Citation
  • About Us
  • Contact Us
  • Natural Products
    Cycloart-22-ene-3,25-diol
    Information
    CAS No. 97456-49-0 Price
    Catalog No.CFN97555Purity>=98%
    Molecular Weight442.7 Type of CompoundTriterpenoids
    FormulaC30H50O2Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)
    Citing Use of our Products
    How to Order
    Orders via your E-mail:

    1. Product number / Name / CAS No.
    2. Delivery address
    3. Ordering/billing address
    4. Contact information
    Sent to Email: info@chemfaces.com
    Contact Us
    Order & Inquiry & Tech Support

    Tel: (0086)-27-84237683
    Fax: (0086)-27-84254680
    E-mail: manager@chemfaces.com
    Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
    Delivery time
    Delivery & Payment method

    1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

    2. We accept: Wire transfer & Credit card & Paypal & Western Union
    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
    Our products had been exported to the following research institutions and universities, And still growing.
  • Universitas Airlangga (Indonesia)
  • University of Hertfordshire (United Kingdom)
  • Lund University (Sweden)
  • Institute of Bioorganic Chemist... (Poland)
  • Imperial College London (United Kingdom)
  • The Vancouver Prostate Centre (... (Canada)
  • Melbourne University (Australia)
  • Colorado State University (USA)
  • Guangzhou Institutes of Biomedi... (China)
  • Universidade Federal de Santa C... (Brazil)
  • University of Toulouse (France)
  • More...
  • Package
    Featured Products
    Isochlorogenic acid A

    Catalog No: CFN99118
    CAS No: 2450-53-5
    Price: $108/20mg
    Isofebrifugine

    Catalog No: CFN92303
    CAS No: 32434-44-9
    Price: $488/20mg
    Terrestrosin K

    Catalog No: CFN90822
    CAS No: 193605-07-1
    Price: $218/10mg
    Ganoderic acid S

    Catalog No: CFN99066
    CAS No: 104759-35-5
    Price: $568/5mg
    Narcissoside

    Catalog No: CFN99773
    CAS No: 604-80-8
    Price: $188/20mg
    Perillen

    Catalog No: CFN90862
    CAS No: 539-52-6
    Price: $168/20mg
    Isochlorogenic acid C

    Catalog No: CFN99120
    CAS No: 32451-88-0
    Price: $100/20mg
    Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
  • Inhibitors Compound Library
  • Triterpenoids Compound Library
  • Tyrosinase Inhibitor Library
  • Biological Activity
    Description: Cycloart-22-ene-3,25-diol shows tyrosinase inhibitory activity, the IC50 value of 77.5 uM .
    Targets: Tyrosinase
    In vitro:
    Chemistry of Natural Compounds, 2014 , 50 (5) :810-3.
    Tyrosinase Inhibitory Activity of Chemical Constituents of Euphorbia macrostegia[Reference: WebLink]

    METHODS AND RESULTS:
    The chloroform extract of the aerial parts of E. macrostegia has yielded a new compound, 2-(4-hydroxyphenyl)-ethylhentriacontanoate (1), along with hentriacontan-1-ol (2), lupenone (3), Cycloart-22-ene-3,25-diol (4), 3,3′,4′-tri-O-methylellagic acid (5), cleomiscosin (6), and glucoclioniasterol (stigmast-5-en-3-O-β-glucopyranoside) (7), and from the ethyl acetate extract of aerial parts of the plant isoquercetin (8), quercetin-3-O-α-arabinofuranoside (avicularin) (9), and rutin (10) have been isolated.
    CONCLUSIONS:
    Compounds 1–10 were tested for their tyrosinase inhibitory activity, and 2 exhibited an IC50 value of 71.4 μM, almost comparable to standard kojic acid (IC50 58.2 μM). Compounds 1–4 also showed good activity with IC50 values of 77.2, 78.6, 71.4, and 77.5 μM, respectively.
    Cycloart-22-ene-3,25-diol Description
    Source: The roots of Astragalus membranaceus
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
    Recent ChemFaces New Products and Compounds
    Ganoderol B

    Catalog No: CFN99064
    CAS No: 104700-96-1
    Price: $368/5mg
    Nodakenin

    Catalog No: CFN90232
    CAS No: 495-31-8
    Price: $138/20mg
    Sibiricaxanthone B

    Catalog No: CFN90644
    CAS No: 241125-81-5
    Price: $238/20mg
    Yadanzioside G

    Catalog No: CFN96422
    CAS No: 95258-17-6
    Price: $413/5mg
    Polygalasaponin E

    Catalog No: CFN95138
    CAS No: 882664-72-4
    Price: $368/5mg
    3,4-O-dimethylcedrusin

    Catalog No: CFN95026
    CAS No: 166021-14-3
    Price: $388/10mg
    Astin A

    Catalog No: CFN95187
    CAS No: 151201-75-1
    Price: $318/10mg
    Naringin 4'-glucoside

    Catalog No: CFN95014
    CAS No: 17257-21-5
    Price: $338/5mg
    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.2589 mL 11.2943 mL 22.5887 mL 45.1773 mL 56.4717 mL
    5 mM 0.4518 mL 2.2589 mL 4.5177 mL 9.0355 mL 11.2943 mL
    10 mM 0.2259 mL 1.1294 mL 2.2589 mL 4.5177 mL 5.6472 mL
    50 mM 0.0452 mL 0.2259 mL 0.4518 mL 0.9035 mL 1.1294 mL
    100 mM 0.0226 mL 0.1129 mL 0.2259 mL 0.4518 mL 0.5647 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.