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    Glycyrrhetic acid 3-O-mono-beta-D-glucuronide
    CAS No. 34096-83-8 Price
    Catalog No.CFN90683Purity>=98%
    Molecular Weight646.8Type of CompoundTriterpenoids
    FormulaC36H54O10Physical DescriptionPowder
    Download Manual    COA    MSDSSimilar structuralComparison (Web)
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    Biological Activity
    Description: 1. Glycyrrhetic acid 3-O-mono-beta-D-glucuronide is a potent sweetener (relative sweetness to sucrose: x 941).
    Glycyrrhetic acid 3-O-mono-beta-D-glucuronide Description
    Source: The roots of Glycyrrhiza uralensis Fisch
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
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    PMID: 29328914

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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.5461 mL 7.7304 mL 15.4607 mL 30.9215 mL 38.6518 mL
    5 mM 0.3092 mL 1.5461 mL 3.0921 mL 6.1843 mL 7.7304 mL
    10 mM 0.1546 mL 0.773 mL 1.5461 mL 3.0921 mL 3.8652 mL
    50 mM 0.0309 mL 0.1546 mL 0.3092 mL 0.6184 mL 0.773 mL
    100 mM 0.0155 mL 0.0773 mL 0.1546 mL 0.3092 mL 0.3865 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Glycyrrhetic acid 3-O-mono-beta-D-glucuronide References Information
    Citation [1]

    Biosci. Biotech. Bioch.,1994, 58(3):554-5.

    Microbial Production of Glycyrrhetic Acid 3--Mono--D-Glucuronide from Glycyrrhizin by MG-27[Reference: WebLink]
    It was found that MG-27, a yeast isolated from soil, selectively hydrolyzed the terminal -glucuronyl linkage of glycyrrhizin (1) to yield glycyrrhetic acid 3--mono---glucuronide (Glycyrrhetic acid 3-O-mono-beta-D-glucuronide,MGGR, 3), a potent sweetener (relative sweetness to sucrose: × 941). The conditions for cultivation of this yeast with the maximum hydrolytic activity as well as the reaction conditions of 1 with the cells for the maximum yield of 3 were investigated. Based on the results, strain MG-27 was cultivated with a medium composed of 1.0% 1, 1.0% glucose, 0.5% Polypepton, and 0.3% yeast extract at 28°C for 24h. The reaction of the resulting cells and 1 at pH 5.7 at 45°C for 48 h afforded 3 in a yield of 95%.