|Source:||The herbs of Gnetum cleistostachynm|
|Biological Activity or Inhibitors:||1. Gnetol has a strong inhibitory effect on murine tyrosinase activity.
2. Gnetol significantly suppresses melanin biosynthesis in murine B16 melanoma cells.
|Solvent:||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.|
|Storage:||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
|After receiving:||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.|
|1 mg||5 mg||10 mg||20 mg||25 mg|
|1 mM||4.095 mL||20.475 mL||40.95 mL||81.9001 mL||102.3751 mL|
|5 mM||0.819 mL||4.095 mL||8.19 mL||16.38 mL||20.475 mL|
|10 mM||0.4095 mL||2.0475 mL||4.095 mL||8.19 mL||10.2375 mL|
|50 mM||0.0819 mL||0.4095 mL||0.819 mL||1.638 mL||2.0475 mL|
|100 mM||0.041 mL||0.2048 mL||0.4095 mL||0.819 mL||1.0238 mL|
Biosci Biotechnol Biochem. 2003 Mar;67(3):663-5.
|Gnetol as a potent tyrosinase inhibitor from genus Gnetum.[Pubmed: 12723623]|
|Gnetol (2,3',5',6-tetrahydroxy-trans-stilbene), a naturally occurring compound particularly found in the genus Gnetum, had a strong inhibitory effect on murine tyrosinase activity. Gnetol (IC50, 4.5 microM) was stronger than kojic acid (IC50, 139 microM) as a standard inhibitor for murine tyrosinase activity. Moreover, Gnetol significantly suppressed, melanin biosynthesis in murine B16 melanoma cells.|