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    Gnetol
    Information
    CAS No. 86361-55-9 Price $388 / 5mg
    Catalog No.CFN92425Purity> 95%
    Molecular Weight244.2Type of CompoundPhenols
    FormulaC14H12O4Physical DescriptionPowder
    Download     COA    MSDS    SDFSimilar structuralComparison (Web)
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    Gnetol Description
    Source: The herbs of Gnetum cleistostachynm
    Biological Activity or Inhibitors: 1. Gnetol has a strong inhibitory effect on murine tyrosinase activity.
    2. Gnetol significantly suppresses melanin biosynthesis in murine B16 melanoma cells.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 4.095 mL 20.475 mL 40.95 mL 81.9001 mL 102.3751 mL
    5 mM 0.819 mL 4.095 mL 8.19 mL 16.38 mL 20.475 mL
    10 mM 0.4095 mL 2.0475 mL 4.095 mL 8.19 mL 10.2375 mL
    50 mM 0.0819 mL 0.4095 mL 0.819 mL 1.638 mL 2.0475 mL
    100 mM 0.041 mL 0.2048 mL 0.4095 mL 0.819 mL 1.0238 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Gnetol References Information
    Citation [1]

    Biosci Biotechnol Biochem. 2003 Mar;67(3):663-5.

    Gnetol as a potent tyrosinase inhibitor from genus Gnetum.[Pubmed: 12723623]
    Gnetol (2,3',5',6-tetrahydroxy-trans-stilbene), a naturally occurring compound particularly found in the genus Gnetum, had a strong inhibitory effect on murine tyrosinase activity. Gnetol (IC50, 4.5 microM) was stronger than kojic acid (IC50, 139 microM) as a standard inhibitor for murine tyrosinase activity. Moreover, Gnetol significantly suppressed, melanin biosynthesis in murine B16 melanoma cells.