|Source:||From Haliclona n. sp.|
|Biological Activity or Inhibitors:||1. Halaminol A and haliclonacyclamine A have similar effects on sponge, polychaete, gastropod and bryozoan larvae, inhibit both settlement and metamorphosis, and prevent fouling and colonisation.
|Solvent:||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.|
|Storage:||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
|After receiving:||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.|
|1 mg||5 mg||10 mg||20 mg||25 mg|
|1 mM||4.3977 mL||21.9887 mL||43.9773 mL||87.9546 mL||109.9433 mL|
|5 mM||0.8795 mL||4.3977 mL||8.7955 mL||17.5909 mL||21.9887 mL|
|10 mM||0.4398 mL||2.1989 mL||4.3977 mL||8.7955 mL||10.9943 mL|
|50 mM||0.088 mL||0.4398 mL||0.8795 mL||1.7591 mL||2.1989 mL|
|100 mM||0.044 mL||0.2199 mL||0.4398 mL||0.8795 mL||1.0994 mL|
Mar Biotechnol (NY). 2009 Mar-Apr;11(2):188-98.
|Convergent antifouling activities of structurally distinct bioactive compounds synthesized within two sympatric Haliclona demosponges.[Pubmed: 18690486]|
|the long chain alkyl amino alcohol, Halaminol A (LA), respectively. Despite structural differences, HA and Halaminol A have identical effects on phylogenetically disparate ascidian larvae, inducing rapid larval settlement but preventing subsequent metamorphosis at precisely the same stage. HA and Halaminol A also have similar effects on sponge, polychaete, gastropod and bryozoan larvae, inhibiting both settlement and metamorphosis. Despite having identical roles in preventing fouling and colonisation, HA and Halaminol Adifferentially affect the physiology of cultured HeLa human cells, indicating they have different molecular targets.|
Natural Product Research,2015, 29(24):1-7
|Characterisation of the metabolites of an antibacterial endophyte Pat. of L. by LC–MS/MS[Reference: WebLink]|
|Botryodiplodia theobromae Pat. belongs to the endophytic fungi that live within the tissues of medicinal plants and produce bioactive natural products. The endophyte was isolated from the leaves of Dracaena draco L. The LC-MS-based metabolite fingerprinting of the ethyl acetate extract of B. theobromae with antibacterial activity led to the identification of 13 metabolites pertaining to various classes: dipeptides (maculosin and L,L-cyclo(leucylprolyl), alkaloid (norharman), coumarin and isocoumarins (bergapten, meranzin and monocerin), sesquiterpene (dihydrocumambrin A), aldehyde (formyl indanone), fatty alcohol (Halaminol A) and fatty acid amide (palmitoleamide, palmitamide, capsi-amide and oleamide). This study reports for the first time, the LC-MS and LC-MS/MS identification of 13 known bioactive metabolites from the antibacterial ethyl acetate extract of B.theobromae isolated from the leaves of D. draco L.|