ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
Citing Use of our Products
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Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / $35.9 / In-stock||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Mol Med Rep.2015, 12(5):7789-95SBRAS2016, 12HortTechnology2016, 26(6):816-819Oncol Rep.2016, 35(3):1356-64Int J Mol Med.2016, 37(2):501-8J Exp Bot.2016, 67(12):3777-88Molecules.2017, 22(12)Biol Pharm Bull.2017, 40(6):797-806
Integr Med Res.2017, 6(4):395-403Journal of Analytical Chemistry...2017...Int J Mol Sci.2018, 19(9):E2825Front Microbiol.2019, 10:2806Nutrients.2019, 11(6):E1380Molecules.2019, 24(20):3755FASEB J.2019, 33(2):2026-2036New Journal of Chemistry...2019...
Psychopharmacology (Berl).2020, 10.1007J Nat Med.2020, 74(1):65-75Nutrients.2020, 12(11):3448. Int J Mol Sci.2020, 21(22):8816. Biosci Rep.2020, 40(8):BSR20201219.Medicina (Kaunas).2020, 56(12):685.Antioxidants (Basel).2020, 9(6):544.
Our products had been exported to the following research institutions and universities, And still growing.
The University of Newcastle (Australia)Monash University (Australia)University of Indonesia (Indonesia)Guangzhou Institutes of Biomedi... (China)
Universite Libre de Bruxelles (Belgium)University of Limpopo (South Africa)Celltrion Chemical Research Ins... (Korea)University of Madras (India)
Universiti Sains Malaysia (Malaysia)Nanjing University of Chinese M... (China)Florida A&M University (USA)
Related Screening Libraries
|Size /Price /Stock
||10 mM * 100 uL in DMSO / Inquiry / In-stock |
10 mM * 1 mL in DMSO / Inquiry / In-stock
||Coumarins Compound Library
|| Cichoriin is a photosensitive compound, it could be used as herbal photosensitizing agent in treating benign breast tumor in rats.|
|International Journal of Biological Chemistry, 2009, 3(1):11-17. |
|Cytoprotective Activity of Chemical Constituents Isolated from Streptomyces sp.[Reference: WebLink]|
METHODS AND RESULTS:
Four flavonoids including kaempferol (1), isoscutellarin (2), umbelliferone (3) and Cichoriin (4) have been isolated from Streptomyces sp. Tc052, an endophyte in the root tissue of Alpinia galanga Swartz. The evaluation for protective effect of compounds 1-4 against glutamate-induced cytotoxicity in hippocampal HT22 cell line was conducted, Compounds 1 and 2 showed significant effective protection ratios of 62.4+2.8 and 55.3+3.4%, respectively, at a concentration of 100 μM, whereas compounds 3-4 were inactive. Compounds 1 and 2 showed potent scavenging effects on DPPH radical exhibiting IC50 value of 60.74 and 75.65 μM, respectively.
These results suggest that compounds 1 and 2 may possess the neuroprotective activity against oxdative cellular injuries.
|Electromagn Biol Med. 2012 Dec;31(4):299-309. |
|Introducing Cichorium Pumilum as a potential therapeutical agent against drug-induced benign breast tumor in rats.[Pubmed: 22812448]|
|Cichorium Pumilum (chicory) is could be a promising cancer treatment in which a photosensitizing drug concentrates in benign tumor cells and activated by quanta at certain wavelength. Such activated extracts could lead to cell death and tumor ablation. Previous studies have shown that Cichorium Pumilum (chicory) contains photosensitive compounds such as
Cichoriin, anthocyanins, lactucin, and Lactucopicrin. |
METHODS AND RESULTS:
In the present study, the protective effect of sun light-activated Cichorium against the dimethylbenz[a]anthracene (DMBA) induced benign breast tumors to female Sprague-Dawley rats was investigated. Chicory's extract has significantly increase P.carbonyl (PC) and malondialdehyde (MDA) and decreases the hepatic levels of total antioxidant capacity (TAC) and superoxide dismutase (SOD) in benign breast tumors-induced group compared to control. It also significantly decrease the number of estrogen receptors ER-positive cells in tumor masses.
These results suggest that chicory extracts could be used as herbal photosensitizing agent in treating benign breast tumor in rats.
||The roots of Cichorium intybus
||DMSO, Pyridine, Methanol, Ethanol, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.