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    Hydroxyevodiamine
    Information
    CAS No. 1238-43-3 Price
    Catalog No.CFN90347Purity>=98%
    Molecular Weight319.36Type of CompoundAlkaloids
    FormulaC19H17N3O2Physical DescriptionYellow powder
    Download     COA    MSDSSimilar structuralComparison (Web)
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    Description: Reference standards.
    Hydroxyevodiamine Description
    Source: The fruits of Evodia rutaecarpa (Juss.) Benth.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

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    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.1313 mL 15.6563 mL 31.3126 mL 62.6253 mL 78.2816 mL
    5 mM 0.6263 mL 3.1313 mL 6.2625 mL 12.5251 mL 15.6563 mL
    10 mM 0.3131 mL 1.5656 mL 3.1313 mL 6.2625 mL 7.8282 mL
    50 mM 0.0626 mL 0.3131 mL 0.6263 mL 1.2525 mL 1.5656 mL
    100 mM 0.0313 mL 0.1566 mL 0.3131 mL 0.6263 mL 0.7828 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    《Spectroscopy and Spectral Analysis》 2007-05
    TLC-SERS Study on Evodiamine in Evodia Rutaecarpa[Reference: WebLink]

    METHODS AND RESULTS:
    A new method for analyzing the ingredients of evodiamine(EV), rutaecarpine(RU), Hydroxyevodiamine(HYD), evodiamide(ED), dihydrorutaecarpine(DRU) and 14-formyldihydrorutaecarpine(FDRU)in evodia rutaecarpa using high performance thin layer chromatography (TLC) and surface enhanced Raman spectroscopy (SERS) technique is reported. The character of this method is that standard samples are not needed . The results show that the characteristic spectral bands of EV, RU, Hydroxyevodiamine, and ED can be obtained from the TLC spot with microgramme of sample. The spectral band at 1 562 cm-1 was obtained with great enhancement. Molecule absorbed in surface silver sol by π electrons in ring.
    CONCLUSIONS:
    The spectral bands of EV, RU, Hydroxyevodiamine and ED are obviously different due to their differences in structure.
    《Natural Product Research and Development》 2004-01
    STUDIES ON THE CHEMICAL CONSTITUENTS OF EVODIA RUTAECARPA VAR. OFFICINALIS[Reference: WebLink]

    METHODS AND RESULTS:
    From the fruits of Evodia rutaecarpa var. officinalis,15 compounds were isolated,and their structures were determined on the spectral evidences as evodiamine(1),rutaecarpine(2),Hydroxyevodiamine(3),14-formyldihydro-rutaecarpine(4),evodiamide(5),goshuyuamide-I(6),dihydroevocarpine(7),skimmianine(8),quercetin-3-O-β-D-galactoside (9),isorhamnetin-3-O-β-D-galactoside(10),rutaevine(11),β-sitosterol(12),daucosterol(13),palmatic acid(14),stearic acid(15),respectively.
    CONCLUSIONS:
    Among them,compound 4~6,8~10 and 12~15 were obtained from this plant for the first time.