• ChemFaces is a professional high-purity natural products manufacturer.
  • Product Intended Use
  • 1. Reference standards
  • 2. Pharmacological research
  • 3. Inhibitors
  • Home
  • Natural Products
  • Bioactive
  • Screening Libraries
  • Hot Products
  • Plant Catalog
  • Customer Support
  • Product Use Citation
  • About Us
  • Contact Us
  • Natural Products
    Isoescin IB
    Information
    CAS No. 219944-46-4 Price $268 / 10mg
    Catalog No.CFN90933Purity>=98%
    Molecular Weight1131.3Type of CompoundTriterpenoids
    FormulaC55H86O24Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)
    How to Order
    Orders via your E-mail:

    1. Product number / Name / CAS No.
    2. Delivery address
    3. Ordering/billing address
    4. Contact information
    Sent to Email: info@chemfaces.com
    Contact Us
    Order & Inquiry & Tech Support

    Tel: (0086)-27-84237683
    Fax: (0086)-27-84254680
    E-mail: manager@chemfaces.com
    Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
    Delivery time
    Delivery & Payment method

    1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

    2. We accept: Wire transfer & Credit card & Paypal & Western Union
    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    Our products had been exported to the following research institutions and universities, And still growing.
  • Mahatma Gandhi University (India)
  • University of Malaya (Malaysia)
  • University of Hawaii Cancer Center (USA)
  • University of Minnesota (USA)
  • Copenhagen University (Denmark)
  • VIB Department of Plant Systems ... (Belgium)
  • Universidad de La Salle (Mexico)
  • University of Bordeaux (France)
  • University of Melbourne (Australia)
  • Kyung Hee University (Korea)
  • Colorado State University (USA)
  • More...
  • Package
    Featured Products
    Linderalactone

    Catalog No: CFN99761
    CAS No: 728-61-0
    Price: $198/20mg
    Scopolin

    Catalog No: CFN98887
    CAS No: 531-44-2
    Price: $168/20mg
    Hannokinol

    Catalog No: CFN96248
    CAS No: 79120-40-4
    Price: $368/5mg
    Isolinderalactone

    Catalog No: CFN99762
    CAS No: 957-66-4
    Price: $238/5mg
    Isochlorogenic acid B

    Catalog No: CFN99119
    CAS No: 14534-61-3
    Price: $108/20mg
    Biological Activity
    Description: Isoescin IB is a natural product from Aesculus hippocastanum L.
    Isoescin IB Description
    Source: The herbs of Aesculus hippocastanum L.
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
    Recent ChemFaces New Products and Compounds
    Licochalcone B

    Catalog No: CFN99576
    CAS No: 58749-23-8
    Price: $328/10mg
    Arjungenin

    Catalog No: CFN95039
    CAS No: 58880-25-4
    Price: $318/10mg
    4,5-Dimethoxycanthin-6-one

    Catalog No: CFN99847
    CAS No: 18110-87-7
    Price: $333/5mg
    Ononin

    Catalog No: CFN99136
    CAS No: 486-62-4
    Price: $148/20mg
    Polyporenic acid C

    Catalog No: CFN92739
    CAS No: 465-18-9
    Price: $333/5mg
    Agnuside

    Catalog No: CFN99203
    CAS No: 11027-63-7
    Price: $158/10mg
    2''-O-Galloylmyricitrin

    Catalog No: CFN95046
    CAS No: 56939-52-7
    Price: $333/5mg
    (-)-Catechin gallate(CG)

    Catalog No: CFN98504
    CAS No: 130405-40-2
    Price: $348/20mg
    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.

    PMID: 29328914

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.

    PMID: 29149595

    Scientific Reports 2017 Dec 11;7(1):17332.
    doi: 10.1038/s41598-017-17427-6.

    PMID: 29230013

    Molecules. 2017 Oct 27;22(11). pii: E1829.
    doi: 10.3390/molecules22111829.

    PMID: 29077044

    J Cell Biochem. 2018 Feb;119(2):2231-2239.
    doi: 10.1002/jcb.26385.

    PMID: 28857247

    Phytomedicine. 2018 Feb 1;40:37-47.
    doi:10.1016/j.phymed.2017.12.030

    PMID: 29496173
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 0.8839 mL 4.4197 mL 8.8394 mL 17.6788 mL 22.0985 mL
    5 mM 0.1768 mL 0.8839 mL 1.7679 mL 3.5358 mL 4.4197 mL
    10 mM 0.0884 mL 0.442 mL 0.8839 mL 1.7679 mL 2.2098 mL
    50 mM 0.0177 mL 0.0884 mL 0.1768 mL 0.3536 mL 0.442 mL
    100 mM 0.0088 mL 0.0442 mL 0.0884 mL 0.1768 mL 0.221 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    Adv Pharm Bull. 2015 Nov;5(4):587-91.
    Determination of Four Major Saponins in Skin and Endosperm of Seeds of Horse Chestnut (Aesculus Hippocastanum L.) Using High Performance Liquid Chromatography with Positive Confirmation by Thin Layer Chromatography.[Pubmed: 26819933 ]
    To separate and quantify four major saponins in the extracts of the skin and the endosperm of seeds of horse chestnut (Aesculus hippocastanum L.) using ultrasonic solvent extraction followed by a high performance liquid chromatography-diode array detector (HPLC-DAD) with positive confirmation by thin layer chromatography (TLC).
    METHODS AND RESULTS:
    The saponins: escin Ia, escin Ib, isoescin Ia and Isoescin IB were extracted using ultrasonic extraction method. The optimized extraction conditions were: 70% methanol as extraction solvent, 80 °C as extraction temperature, and the extraction time was achieved in 4 hours. The HPLC conditions used: Zorbax SB-ODS-(150 mm × 2.1 mm, 3 μm) column, acetonitrile and 0.10% phosphoric acid solution (39:61 v/v) as mobile phase, flow rate was 0.5 mL min(-1) at 210 nm and 230 nm detection. The injection volume was 10 μL, and the separation was carried out isothermally at 30 °C in a heated chamber. The results indicated that the developed HPLC method is simple, sensitive and reliable. Moreover, the content of escins in seeds decreased by more than 30% in endosperm and by more than 40% in skin upon storage for two years.
    CONCLUSIONS:
    This assay can be readily utilized as a quality control method for horse chestnut and other related medicinal plants.