ChemFaces is a professional high-purity natural products manufacturer.
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1. Reference standards
2. Pharmacological research
Citing Use of our Products
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / $413 / In-stock||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Mol Cells.2015, 38(9):765-72Food Chem.2016, 191:81-90Mediators Inflamm. 2016, 2016:6189590Food Sci Biotechnol....2016...Free Radic Biol Med.2017, 112:191-199Nat Prod Commun.2017, 12(5):771-778J of L. Chroma.&Related Tech...2017...Journal of Functional Foods...2017...
J.Acta Agriculturae Scandinavica...2017...J Agric Food Chem....2017...PLoS One.2018, 13(3):e0193386Integr Cancer Ther.2018, 17(3):832-843Phys Chem Chem Phys....2018...Front Neurosci.2019, 13:1091Microb Pathog.2019, 131:128-134J Pharm Biomed Anal.2019, 164:119-127
BMC Microbiol.2019, 19(1):78Molecules.2019, 24(10):E1930FASEB J.2019, 33(2):2026-2036Int Immunopharmacol.2019, 71:361-371Plant Foods Hum Nutr.2020, 10.1007Pharmacological Reports2020, 1-9Biochem Biophys Res Commun....2020...
Our products had been exported to the following research institutions and universities, And still growing.
Monash University Sunway Campus (Malaysia)Johannes Gutenberg University M... (Germany)Technical University of Denmark (Denmark)National Cancer Center Research... (Japan)
University of Auckland (New Zealand)University of Perugia (Italy)Indian Institute of Science (India)Donald Danforth Plant Science C... (USA)
Chulalongkorn University (Thailand)Universitas islam negeri Jakarta (Indonesia)Utrecht University (Netherlands)
Related Screening Libraries
|Size /Price /Stock
||10 mM * 100 uL in DMSO / Inquiry / In-stock |
10 mM * 1 mL in DMSO / Inquiry / In-stock
||Phenols Compound Library
||Pilosidine has vasoconstrictor activity, it showed facilitating effect on adrenaline evoked contractions in rabbit aorta isolated preparations.|
|Phytochemistry, 2000, 55(5):411-417. |
|Benzylbenzoate and norlignan glucosides from Curculigo pilosa: structural analysis and in vitro vascular activity[Pubmed: 11140602 ]|
METHODS AND RESULTS:
From the rhizomes of Curculigo pilosa, two benzylbenzoate diglucosides, piloside A and piloside B, and a glucosyl-fused norlignan, Pilosidine, previously obtained only as the tetra-O-methyl derivative, were isolated.
Pilosidine showed facilitating effect on adrenaline evoked contractions in rabbit aorta isolated preparations.
||The herbs of Curculigo capitulata
||DMSO, Pyridine, Methanol, Ethanol, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|Farmaco. 2001 May-Jul;56(5-7):353-6. |
|Studies on vasoconstrictor activity of Curculigo pilosa extracts and of its isolated compounds.[Pubmed: 11482757]|
METHODS AND RESULTS:
The Curculigo pilosa total extract, its butanolic fraction (0.5 microg-100 mg/kg) and the most active in vitro compound structurally similar to adrenaline, Pilosidine (10 ng-l mg/kg), caused a reversible and dose-dependent increase in blood pressure in anaesthetized rat. This hypertensive effect is partially reversed (90%) by the prior administration of phentolamine (1 mg/kg) and abolished by pre-treatment with phentolamine (1 mg/kg) and atenolol (100 microg/kg). Neither tachiphylaxis nor any toxic effects were observed.
These experimental findings suggest an interaction between C. pilosa and the peripheral adrenergic system (particularly with alpha1 and beta1 receptors); the structure of the bioactive glucosides could be important in evoking this effect.